STUDY OF ACUTE KIDNEY INJURY IN SNAKE BITE PATIENTS
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 35
Abstract
BACKGROUND Snake venom is well known to cause toxic damage to the kidneys (Schreiner and Maher, 1965). This study is an attempt to evaluate the snakebite-induced Acute Kidney Injury (AKI). MATERIALS AND METHODS 50 patients with snakebite-induced acute kidney injury were selected randomly and their clinical profile was assessed. Acute kidney injury was evaluated using noninvasive laboratory methods. Inclusion Criteria- 1. History of snakebite; 2. Presence of AKI. Exclusion Criteria- Pre-existing renal diseases, after establishing the diagnosis, patients were started on conservative treatment including ASV, blood/blood products and haemodialysis as required. RESULTS Out of 50 patients included in the study, majority of them were males (62%) with mean age of presentation 43.8 ± 12.63 years. The mean interval between snakebite and presentation to hospital was 15.37 hours. In them, 98% patients presented with local signs of inflammation, 52% of patients presented with coagulation abnormality and 60% with decreased urine output. Comparison between good outcome (recovered from AKI) and poor outcome (not recovered from AKI) shows significant pvalue for ‘lapse of time in hours’ in presenting to the hospital after snakebite (p value 0.005) and ‘alternative treatment taken’ before coming to the hospital (p value 0.001). CONCLUSION Poisonous snakebites have common manifestations of cellulitis, abnormal coagulation profile and decreased urine output. Overall mortality due to snakebite-induced AKI is 6%. Patients who did not recover from AKI had lapse of time in presenting to the hospital and abnormal coagulation profile.
Authors and Affiliations
Suma Dasaraju
Keywords
Related Articles
- EP ID EP218895
- DOI 10.18410/jebmh/2017/413
- Views 86
- Downloads 0
A STUDY OF PERIOPERATIVE HAEMODYNAMIC ASSESSMENT BY NICOM (NON INVASIVE CARDIAC OUTPUT MONITORING) IN PARTURIENT POSTED FOR CAESAREAN SECTION UNDER SUBARACHNOID BLOCK
Pregnancy is a state of dramatic haemodynamic changes to accommodate the increasing needs of a pregnant body. These changes can be further complicated by preeclampsia which occurs in 6-12% of all pregnancies, showing var...
STUDY EVALUATION OF URINE PROTEIN/URINE CREATININE RATIO FOR QUANTIFICATION OF PROTEINURIA IN RAPID AND RELIABLE DIAGNOSIS OF NEPHROTIC SYNDROME
BACKGROUND Nephrotic syndrome is a common renal disease in 2-6-year-old children characterised by proteinuria, hypoalbuminemia, oedema and hypercholesterolemia. Incidence is 2-3 /1 lakh children per year. Without treatme...
CLINICO-SEROLOGICAL PROFILE AND DISEASE SEVERITY IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) ATTENDING A TERTIARY CARE CENTRE IN CENTRAL KERALA
BACKGROUND Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease characterised by the production of multiple autoantibodies. There is limited available data regarding the presentation patterns of SLE in...
ROLE OF C REACTIVE PROTEIN AND WBC COUNT IN THE DIAGNOSIS OF ACUTE APPENDICITIS AND ITS PREDICTIVE VALUE IN ASSESSING THE SEVERITY OF THE DISEASE
BACKGROUND Acute appendicitis is still one of the commonest surgical emergencies. The clinical experience of the surgeon decides the accuracy of the diagnosis which is difficult in 30-40% of cases despite available diagn...
EFFECTS OF INTEGRATED APPROACH OF YOGA (IAY) ON ESSENTIAL HYPERTENSION
The present study was designed to find out the effects of Integrated Approach of Yoga (IAY) on Essential Hypertension in a sample of 120 subjects from Cardiology OPD of AIIMS, Bhubaneswar in the age group of 21 years to...