Study of antimicrobial sensitivity and resistance of pathogens isolated from postoperative wound infection
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2014, Vol 3, Issue 3
Abstract
Surgical site infection are the third most common type of healthcare acquired infections in hospitals. SSI are the most common nosocomial infection in surgical patients, contributing to perioperative morbidity, prolonged postoperative hospital length of stay, and increased hospital costs. Emergent of pathogens and rapid growth of multi- drug resistance demands periodic review of isolation patterns and its sensitivity. Hence, the present study was aimed to study the antimicrobial sensitivity and resistance of some pathogens isolated from postoperative wound infection. The study was carried out in a 1400 bedded multi-specialty tertiary care teaching hospital attached to Annamalai University. Clinical specimens were collected from the patient and cultured in the appropriate media. Isolated colonies were subjected to gram staining technique and biochemical tests for identification. Antibiotic sensitivity tests were carried out on isolated and identified colonies using commercially prepared antibiotic sensitivity disc using Kirby-Bauer method. Totally 341 surgeries were carried out during the study period and about 46 surgical site infection were observed. Study results showed the following (a) Of all pathogens, Staphylococcus aureus and Pseudomonas aeruginosa were more prevalent whereas, Klebsiella and Escherichia coli were moderately prevalent and Proteus mirabilis was least prevalent, (c) Of all antibiotics, Amikacin was sensitive to all pathogens in the study with low resistance profile.
Authors and Affiliations
R. T. Saravanakumar
Keywords
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