Study of Clinical Profile in Patients with H1N1 Influenza in New Civil Hospital Surat, January 2015-September-2015
Journal Title: International Journal Of Research In Medicine - Year 2017, Vol 6, Issue 1
Abstract
BACKGROUND: We describe the clinical profile of patients who were found H1N1 Positive in new civil hospital Surat from 1st January 2015 to 30 September 2015. MATERIAL &METHODS: Retrospective data of 152 patients from New Civil Hospital Surat who were suspected with influenza like illness was collected. They were subjected to throat swab testing for H1N1. Out of them 60 were positive for H1N1 virus with use of real time reverse transcriptase polymerase chain reaction assay. (TAQ MAN real time PCR CDC protocol).Clinical parameters of these 60 patients were analyzed. RESULTS: Out of 152 suspected H1N1 influenza patients, 60 (39.47%) patients were confirmed (positive) for H1N1.Male 33(55%) were affected more than females 27(45%). 23(37.66%) patients had underlying Co-Morbid condition. Fever (98.70%) and cough (100%) were the most common presenting symptom. Total 18 (30%) patients were put on mechanical ventilator. Out of the 60 patients, 20 patients who received oseltamivir within 72 hour of onset of illness, 18 (90%) were cured and 2(10%) expired. 40 Patients who had received oseltamivir after 72 hrs 30(75%) cured and 10(25%) expired . We observed no significant adverse effect of oseltamivir 150 mg twice day dose for 5-7 days. CONCLUSIONS: Maximum patients were between age group of 14-50 year. Fever and cough were most common presenting symptoms. Mechanical ventilatory support had role in reducing mortality. Patients seemed to be benefited more from antiviral therapy if started within 72 hour of onset of symptom. There were no significant adverse effects of Oseltamivir observed in this study. Development of ARDS, requirement of Mechanical ventilation and having co-morbid condition were poor prognostic factors.
Authors and Affiliations
Sweta Gamit, Ashvin Vasava, Ketan Patel, Amit Gamit, Tinkal Patel
Keywords
Related Articles
- EP ID EP437613
- DOI -
- Views 111
- Downloads 0
Urine analysis findings of malaria patients attending tertiary care hospital of North Gujarat
BACKGROUND: Vector borne diseases are emerging health problems in developing countries. Among all of vector borne diseases, malaria remains at the top especially during rainy seasons. Plasmodium vivax and plasmodium fal...
Sample Rejection Rate in Clinical Biochemistry Laboratory of a Tertiary Care Centre
BACKGROUND: Recent publications have reported that up to 70 % of total laboratory errors occur in the pre analytical phase. Many times samples have to be rejected in laboratory without analysis. The common causes of reje...
Situational analysis of Bio-medical waste management of Tertiary care centre and Common Bio-medical Waste Treatment Facility of South Gujarat
BACKGROUND INCLUDING OBJECTIVES: A legislative framework for Bio-medical waste management was generated a decade ago; but still there is a gap at local level in management. So, this study was planned to document existing...
Study of Correlation of Clinical Profile, Electrocardiographic and Echocardiographic Profile in Patients of Chronic Obstructive Pulmonary Disease and Cor-Pulmonale
BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a major cause of chronic morbidity and mortality throughout the world. COPD is currently the 4th leading cause of death in the world. This study was undertaken...
Anti-Tuberculosis Treatment Induced Hepatitis – A Study of Incidence of Recurrence of Hepatitis and Treatment Outcome after Reintroduction of Anti-Tubercular Drugs
BACKGROUND AND OBJECTIVES: Antituberculosis drug-induced hepatotoxicity (ATDH) causes substantial morbidity and mortality and diminishes treatment effectiveness. Asymptomatic transaminase elevations are common during ant...