Study of coagulation profile in hepatic disorders in a Tertiary Care Centre
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 3
Abstract
Introduction: Liver plays the important role of synthesis of coagulation and anti coagulation proteins. Thus derangement of liver functions can lead to alteration and abnormal balance of these pathways. Materials and Methods: The study included 170 cases of diagnosed liver diseases in the gastroenterology ward. PT, APTT and platelet count were the parameters evaluated. Results: Out of the total 170 cases, 130 (76.50%) cases had altered coagulation profile. Out of 115 cases of liver cirrhosis, PT, APTT and platelet count were altered in 71.3%, 81.7% and 52.2% respectively. In 24 cases of liver abscess, PT, APTT and platelet count were altered in 58.3%, 58.3% and 4.1% respectively. In the remaining 31 cases, PT, APTT and platelet count were altered in 40%. 36.7% and 12.9% respectively. Conclusion: Coagulation profile was found to be significantly altered in patients with liver disease.
Authors and Affiliations
Takutila M Ozukum
Keywords
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