Study of Different Doses of Gabapentin for Post-Operative Pain Relief after Laparoscopic Cholecystectomy
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 4
Abstract
This is a prospective, randomized, double blind, placebo controlled study conducted at Yashoda Superspeciality Hospital, Secunderabad, Telangana, India over 160 patients who underwent elective lap cholecystectomy during the period of 1st September 2015 – 30th May2016. Hospital Ethical Committee approval was taken prior to start this study. Sample size was calculated basing on the pilot study and keeping dropouts in mind total sample was decided 40 in each group. Sample size of 40 patients each, randomly allocated into four groups, using computer generated random number list. They were given tab. gabapentin 2hrs before surgery with sips of water. Group 1(Placebo), Group 2(GP-100mg), Group3 (GP-200mg), Group 4 (GP-300mg). Oral Gabapentin 300 mg may be the optimal preoperative dose to reduce the severity of postoperative pain and has an opioid sparing effect after laparoscopic cholecystectomy. At this dose it is well tolerated and may be used as part of multimodal analgesia to improve the quality of postoperative pain relief.
Authors and Affiliations
Dr. Nanda Kumar Murari, M. D, Dr. Venugopal Dageti, M. D, Dr. David, M. D
Keywords
Related Articles
- EP ID EP475792
- DOI -
- Views 63
- Downloads 0
Isolated Muscular Cysticercosis: A Rare Presentation of a Common Helminth
Cysticercosis is a parasitic disease caused by Taenia solium, a common public health problem in developing countries. Infection occurs due to the ingestion of raw or undercooked meat that contains the cysticercus. After...
The Difference Between Physalin Standardized Extract from Pysalis Angulata. L and Control on Pancreatic Function of Sprague Dawley Rat Induced by Streptozotocin-Nicotinamide
Abstract: Diabetes mellitus (DM) is a metabolic disorder of carbohydrate, fat, and protein characterized by chronic hyperglycemia conditions. Oxidative stress due to hyperglycemia in patients with diabetes may fasten the...
Study of Prevalence of Anaemia in Patients with Type 2 Diabetes Mellitus
In type 2 diabetes mellitus, anemia is progressively more recognized entity and can lead to serious morbidity in patients with diabetes. The present study was done to find out the prevalence of anemia in patients with ty...
Platelet-Rich Fibrin to Induce Apical Closure in an Immature Multi-Rooted Permanent Tooth with Necrotic Pulp: A Case Report
Regenerative endodontic procedures are the emerging techniques for the restoration of functional pulp and dentine. The case report presented here describes the management of a symptomatic mandibular first molar with an i...
Effective Teaching from Medical Basic Sciences Faculty Members’ Perspective: A qualitative Study
Teaching is one of the most important components of education around the world is very complex and multi- dimensional. So there is no agreement on its nature and effectiveness. Because of the importance and role of teach...