Study of Efficacy and Safety of Ormeloxifene in Management of Abnormal Uterine Bleeding
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 2
Abstract
Introduction: Abnormal uterine bleeding (AUB) is one of the most common conditions for which women consult their gynaecologists. Study was done to evaluate the efficacy and adverse reactions of ormeloxifene in patients with abnormal uterine bleeding. Material and Methods: This was single centred, open label, 6 months prospective study. 53 patients with complaints of abnormal uterine bleeding having PBAC Score more than 100 were enrolled in study. Ormeloxifene 60mg twice a week was given for 3 months followed by 60 mg once a week for next 3 months. At follow ups, patients were assessed for Endometrial thickness by USG, Haemoglobin level, PBAC score and adverse effects of drug therapy. Results: A total 53 patients with the mean age of 32.91±6.82 were enrolled, in which 45 patients completed the follow up. There was statistically significant decrease in endometrial thickness, haemoglobin level and PBAC score. Conclusion: Thus Ormeloxifene, a non-steroidal, nonhormonal agent, with its convenient dose schedule provides effective and favourable medical treatment.
Authors and Affiliations
Tajinder Kaur, Rakesh C. Chaurasia, Amrita Chaurasia
Keywords
Related Articles
- EP ID EP429616
- DOI -
- Views 115
- Downloads 0
Our Experience of Blood Transfusions in Patients with Moderate Anemia Undergoing Elective Cesarean Sections at Government Medical College, Ananthapuramu
Introduction: Anemia during pregnancy increases the incidence of preterm labor, preeclampsia, sepsis. Anemia also effects fetal outcome in the form of preterm baby, IUGR, increased mortality rate. The aim of the present...
Etiological Study of Respiratory Distress in Newborn
Introduction: Respiratory distress is one of the commonest disorder encountered within the first 48-72 hours of life. Clinical presentation of respiratory distress in newborn include one or more of the following features...
Mean Platelet Volume and Other Platelet Volume Indices in Acute Myocardial Infarction (AMI) and Stable Coronary Artery Diseases (SCAD): A Hospital Based Prospective Observational Study
Introduction: Myocardial infarction is the major cause of morbidity and mortality in industrialized countries. Platelet activation is a hallmark of acute coronary syndrome. An increased MPV, an indicator of larger and mo...
Clinico-Pathological Study and Management of Benign Breast Lesions
Introduction: Benign breast disorders and diseases encompasses a wide range of clinical and pathologic entities. Benign breast diseases include all nonmalignant conditions of the breast and typically do not convey an inc...
Dental Caries in Primary and Permanent Molars in 7-8-Year Old School Children Evaluated with Caries Assessment Spectrum and Treatment (CAST) Index from Bangalore North
Introduction: Caries is a common biofilm-mediated chronic disease that affects all ages. So, the study was done to evaluate caries in primary and first permanent molars of 7-8-year-old children by the Caries Assessment S...