Study of glycolic acid and salicylic acid peels as a sole therapy in treatment of acne vulgaris
Journal Title: International Journal of Medical Research and Review - Year 2016, Vol 4, Issue 12
Abstract
Introduction: Acne vulgaris is a very common physiological condition of adolescents, better regarded as a disease due to some inflammatory component. In spite of various modalities of treatment available, it still poses a therapeutic problem to the dermatologists. The advent of new and potent topical therapeutic modalities such as chemical peeling has resulted in significant improvement in the treatment of acne. This study aims to observe the therapeutic response of two chemical peels, 35% glycolic acid and 30% salicylic acid on active acne lesions, when given as monotherapy. Materials & Methods: A total of 200 patients of either sex with acne were randomly selected and enrolled for the study, two groups of 100 patients each were made of 35% GA and 30% SA respectively. No other concurrent therapy was given. Individual lesions of each type were calculated before and after completing 6 treatment sessions and the numbers were observed to know the effect of both the acids on different types of lesions. Results: After 6 sessions, in the glycolic acid group the reduction in average number of comedones was 88.45%, inflammatory papules 88.65%, pustules 89.62% & nodules/cysts 83.33%. Whereas, in the Salicylic acid group, the reduction was 89.00%, 90.36%, was 84.87% & 100% in comedones, papules, pustules & nodules/cysts respectively. Conclusion: In our observation, both 35% glycolic acid and 30% salicylic acid are significantly effective as monotherapy in patients of acne. They not only clear the acne lesions but also show improvement in post acne scar and hyperpigmentation to some extent.
Authors and Affiliations
Parikshit Sharma, Akhil Shah, Alamjit singh Dhillon
Keywords
Related Articles
- EP ID EP231925
- DOI 10.17511
- Views 120
- Downloads 0
Pattern of anemia in geriatric patients- A hospital based prospective study
Introduction: Anaemia is common in elderly age group and is overlooked as the symptoms such as fatigue, weakness, shortness of breath may be attributed to the ageing process itself but decline in the haematological param...
Study of renal function test in asphyxiated newborns and their outcome
Introduction: There is a high incidence of acute kidney injury (AKI) among asphyxiated term. AKI manifests by changes in urine output and blood chemistries & can have serious clinical consequences. Oliguria has been repo...
Sinonasal Teratocarcinosarcoma
Sinonasal Teratocarcinosarcoma (SNTCS) is an extremely rare and unusual malignant neoplasm of the sinonasal tract with an aggressive behaviour. Till date, there are less than a hundred cases reported in literature. A 52...
Morphologic study of nutrient foramina in dried tibia and its clinical implications
Introduction: Diaphyseal fractures of tibia cases are common in orthopaedics and traumatology department. While planning a bone graft for a patient with trauma or tumour resection, the vascularity of the left over bone i...
Readdressing the role of therapeutic drug monitoring for antiepileptic drugs – A tertiary care hospital experience
Background: Therapeutic drug monitoring is a beneficial tool to supervise patients when they do not respond to a therapeutic dose. Inter individual variability in the concentration of an antiepileptic drug that produces...