Study of hematological profile in sickle cell patient.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Background: Sickle cell disease is one of the most common autosomal recessive diseases in the world caused by a single nucleotide substitution (GTG - GAG) and is located at the sixth codon of the human-globin gene. Aims & Objectives: This study was designed to study hematological profile in sickle cell patient and compare hematological profile in sickle cell traits with sickle cell disease patient Materials and Methods: This study is an observational study done in 70 sickle cell patients in steady state, at Acharya VinobaBhave Rural Hospital, Sawangi Meghe, Wardha, MaharashtraIndia. The complete blood counts (CBC) were analyzed using the Automated Coulter Counter & Sickling pattern were identified on Hbelectrophoresis, at a pH of 8.6oncellulose acetatepaper. Results: Haemoglobin concentration and the MCV was significantly low (≤0.05) in sickle cell diseased patients as compared to sickle cell traits. TLC count was not significantly higher while platelets & red cell distribution width (RDW) were significantly higher (≤0.05) in sickle cell disease (SCD) patients, as compared to traits. Conclusion: Our study has explained haematological parameters & their role in sickle cell trait and sickle cell diseased which could be used in designing of the better management of sickle cell patients.
Authors and Affiliations
Suchita D Modi, Vikas R Agrawal, Arvind S Bhake, Anil Agrawal
Keywords
Related Articles
- EP ID EP362403
- DOI 10.9790/0853-1702068285
- Views 54
- Downloads 0
Primary extragastrointestinal stromal tumor arising In the pancreas: report of a case
Primary extra-gastrointestinal stromal tumor (EGISTs) arising in the pancreas is extremely rare: only 32 cases have previously been reported in the English literature. We report a further case of EGIST of the pancreas. A...
A Study of Association between Lipid Profile and Thyroid Hormones in Pregnancy
Background: To study the association between lipid profile and thyroid hormones in early pregnancy Aims:To investigate lipid profiles and thyroid hormones, US -TSH , FT4, FT3 during early pregnancy. To find out the assoc...
Significance of Body Mass Index In Relation To Renal Dimensions by Using Ultrasonography- A Clinical Study
Objective: The Present Study Is A Sincere Effort On Morphometric Study Of Kidney In Healthy Subjects Using Various Parameters (Length, Width, Cortical Thickness, Renal Size And Renal Volume) Of Right And Left Kidneys In...
Granulomatous Mastitis – Diagnosis and Treatment Modality – Case Report and Review of Literature
Granulomatous mastitis (GM) is an uncommon chronic inflammatory disease of breast of undetermined etiology. Despite its low incidence, it has gained importance since it mimics breast carcinoma. There is still no definite...
Efficacy of Classical Siddha External Therapy “Suttigai” (Thermal Cauterization) On Azal Keel Vaatham
India is one of the very few countries in the world known for its rich heritage of local health traditions. With such a vast knowledge in Ethno Medicine it should be a dynamic approach to use the knowledge base of Tradit...