Study of Lipase Amylase Ratio in Acute Pancreatitis
Journal Title: Indian Journal of Genetics and Molecular Research - Year 2018, Vol 7, Issue 2
Abstract
Aim: The aim of our study was to estimate serum Amylase and serum Lipase levels and to establish a correlation between Lipase/Amylase Ratio in Acute Pancreatitis using lipase and Amylase as enzymatic markers. Study Design: A hospital based cross sectional study was conducted on patients attending the Out patient department of Medicine and those visiting the emergency of SGRRIM & HS Dehradun Uttarakhand for a period of 6 months from April 2017 to September 2017. A total of 130 cases (70 Male & 60 Female) and an equal no. of controls (130) (70 Male & 60 Female) in the age group 20-80 years were selected randomly for the study. Exclusion criteria was age less than 20 years & more than 80 years, acute trauma, Diabetes mellitus, dyslipidaemia, End stage Renal disease etc. Methodology: 5 ml blood was collected in sterile containers form all the 260 subjects and was analyzed for serum Amylase and serum Lipase on fully automated Biochemical Analyzer 5600 of Orthodiagnostics. Results: The mean values of Lipase levels were found to be much higher in male cases (834.83 ± 407.37 ± 47.70) as compared to male controls (97.34 ± 51.71 ± 5.98). Similarly, the mean values of serum Amylase were higher in male cases (233.73 ± 116.69 ± 13.66) than male controls (65.81 ± 24.63 ± 2.85). The Lipase/Amylase ration in male cases was (6.92 ± 3.16 ± 0.37), whereas in male controls it was (1.53 ± 0.71 ± 0.08). Thus the level of Lipase/Amylase ratio is higher in male cases than controls.
Authors and Affiliations
Diksha Mishra
Keywords
Related Articles
- EP ID EP630521
- DOI 10.21088/ijgmr.2319.4782.7218.2
- Views 91
- Downloads 0
Effect of the Epigenetic Regulators (JAK2 and IDH-2) on the Methylation Status of Tumor Suppressor Genes (p15, FHIT, Calcitonin and SOCS-1) and Prognosis of MDS Patients: A Study from India
The Myelodysplastic Syndromes (MDS) are a group of clonal disorders of the hematopoietic system characterized by the presence of ineffective hematopoiesis, peripheral cytopenias and an increased risk of transformation to...
Congenital Heart Defects and Genetic Syndromes
Congenital heart defects may be because of genetic and or environmental factors. Genetic could be Mendelian and non-Mendeliandisorders resulting in syndromes. Aim: The paper reports the identified Mendelianand non-mendel...
Hepatitis C Virus and its Genotypes detection in Serum Specimens: Clinical Relevance for the Management
In India, the cases of Hepatitis C Virus are increasing at a very rapid rate. Hepatitis C virus (HCV) often causes persistent infection, and is important factor in the cirrhosis and hepatocellular carcinoma (HCC). Curren...
Molecular Characterization of Chikungunya Virus in Serum- Relevance for Disease Management
Background: Chikungunya Virusis a single stranded RNA virus of the genus alphavirus. The transmission of this virus occurs by the bite of infected mosquitoes. It is characterized by an brupt onset of fever frequently ac...
Perrault Syndrome: A Rare Cause of Primary Amenorrhoea
Perrault syndrome is an autosomal recessive disorder with sensorineural hearing loss in both female and male, and gonadal dysgenesis in female only. We present here a case which presented to our gynae department with com...