Study of Lipid Profile in Patients with Chronic Kidney Disease on Conservative Management and Hemodialysis
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 7
Abstract
Background: Chronic renal failure results in profound lipid disorders which stem largely from the deregulation of high-density lipoproteins (HDL) and triglyceride-rich lipoprotein metabolism which increases the risk of arteriosclerotic cardiovascular disease which is the leading cause of mortality among chronic kidney disease (CKD) patients. Materials and Methods: This is a cross-sectional observational study conducted after ethical committee approval about lipid profile on CKD patients on conservative management and hemodialysis compared with normal healthy controls at our hospital and movement for global mental health between June 2015 and June 2016, after considering inclusion and exclusion criteria. Lipid profile was collected from eligible patients and controls. Results: There were a statistically significant decrease in HDL and increase in thyroglobulin, low-density lipoprotein (LDL), and total cholesterol levels when compared with normal healthy controls. There was a negative correlation between serum creatinine and HDL levels. Among CKD patients, there was a significant decrease in HDL and increase in LDL level in both conservative and hemodialysis groups. Conclusion: Treatment of dyslipidemia helps to decrease mortality in CKD patients.
Authors and Affiliations
K Rajani Kumari, Bingi Srinivas
Keywords
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