Study of Non-alcoholic Fatty Liver Disease and its Association with Coronary Artery Disease
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 7
Abstract
Introduction: Non Alcoholic fatty liver disease (NAFLD) is a variety of fatty liver which occurs due to hepatic steatosis, caused by other than excessive alcohol use. Data suggests that NAFLD is also an independent risk factor of cardiovascular disease, which remains the commonest cause of mortality in such patients. This study was conducted to estimate the prevalence of NAFLD diagnosed by ultrasound examination of the liver in type 2 diabetes mellitus (DM). Secondary objective was to demonstrate association between NAFLD and coronary artery disease (CAD) in type 2 DM. Material and methods: This was an observational study conducted at Department of General Medicine of a tertiary care centre for 2 years. 500 adult patients (age >18 years) of type 2 DM were evaluated for NAFLD, CAD and other cardiovascular risk factors. Microsoft Excel software and SPSS version 20 for Windows were used for data storage and analysis. Results: The incidence of NAFLD was 44% in all diabetics, among them males were affected more (50%) than females (40%). Mean BMI was 27.8 and 27.2 among males and females respectively. NAFLD subjects had higher incidence of smoking, hypertension, obesity, dyslipidemia, uncontrolled sugar and CAD than Non-NAFLD group subjects. These differences were statistically significant. Conclusion: We should have high index of suspicion of NAFLD in diabetics. Possibility of NAFLD increases if patients have metabolic syndrome. If found, we should manage risk factors for CAD aggressively as patients have high chances of developing CAD in diabetics with NAFLD
Authors and Affiliations
Nikhil Bakhtar, Sarvagya Mishra, Abhishek Singhai, Rajesh kumar Jha
Keywords
Related Articles
- EP ID EP426520
- DOI -
- Views 133
- Downloads 0
Study of Relationship among Hypertension, Overweight and Obesity in Individuals of Different Age Groups
Introduction: Hypertension is a leading cause of morbidity and mortality throughout the world. The age and sex specific cut-offs for diagnosis of hypertension vary in different parts of the world. The diagnosis of childh...
Standardised Physiotherapy Strategies For Chronic Repetitive Ulnar Nerve Compression Injury: A Case Report
Introduction: This case report demonstrate the physiotherapy treatment strategies as a non-invasive functional treatment for chronic nerve degeneration due to repeated compression injury to the ulnar nerve. Case report:...
Solitary Infantile Myofibromatosis at Distal end of Humerus: A Rare Case Report
Introduction: Infantile myofibromatosis is a rare benign disorder of mesenchymal origin presenting as tumors in skin, muscles,bones and soft tissue of head and neck. Its solitary occurrence in bones is very rare. It is e...
Correlation between Body Mass Index and Blood Glucose Levels in Jharkhand Population
Introduction: Obesity is the leading factor in the pathogenesis of health disorders such as hypertension and type-2 diabetes mellitus. Since BMI is the associated with obesity, the present study has been carried out to e...
Prevalence and Association of Hyperuricemia in Patients of Newly Diagnosed Essential Hypertension
Introduction: Essential hypertension (80-95%) is more common than secondary hypertension (5-20%). The prevalence of essential hypertension increases with age. Serum uric acid is thought to play a pathogenic role in devel...