Study of Pituitary Adenomas with Clinical, Radiological, Cytological and Histological Correlation
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 9
Abstract
Pituitary tumours are a common type of intracranial neoplasm and, depending on the cell type of origin, have diverse endocrine and reproductive effects. Most of them are asymptomatic, however a minor portion of 10% of the tumors are symptomatic. Classification of tumors is based on the staining properties of the cell cytoplasm in to three morphologic entities: Chromophobic adenomas, acidophilic adenomas and Basophilic adenomas. The pituitary adenomas are either clinically functioning adenomas or non-functioning adenomas. The former includes GH secreting (cell) adenomas (abbreviated as GHomas), prolactin (PRL) secreting (cell) adenomas (PRLomas), TSH secreting (cell) adenomas (TSHomas), ACTH secreting (cell) adenomas (ACTHomas), and FSH secreting (cell) adenomas (FSHomas) [2]. Radiological studies have shown a prevalence of about 22.5%. Majority of the tumors are benign, a few of them have invasive behavior with rarer few metastasizing.Pituitary carcinoma is very rare. Metastatic carcinoma to the pituitary is sometimes seen, its autopsy findings are not extremely rare and common primary sites include carcinoma of the lung[2]. The present study reviews various pituitary adenomas encountered and aims to study their cytological, histomorphological and clinical characteristics.
Authors and Affiliations
Dr. M. Lavanya, Dr. Sri Lakshmi Gollapalli, Dr. N. Swapna
Keywords
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