Study of Serum Vitamin D Level among Critically Ill Patients Admitted to Alexandria University Pediatric Intensive Care Unit
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 4
Abstract
Background: Vitamin D is a pleiotropic hormone that plays an important role in calcium homeostasis, bone health, cardiovascular system and immunity. Vitamin D has other roles in the body, including modulation of cell growth, neuromuscular and immune functions, and reduction of inflammation. Its deficiency may aggravate the incidence and outcome of infectious complications in critically ill patients. Aim: The aim of this work was to determine the frequency of vitamin D deficiency in critically ill patients admitted to pediatric intensive care unit [PICU], Alexandria university children's hospital (AUCH) and relate the state of serum 25(OH) D to disease severity. Methods: Study was carried out on 102 critically ill children admitted to PICU at AUCH. Blood was collected on PICU admission and analyzed for 25(OH) D concentration by using enzyme linked immunosorbent assay (ELISA) kits. Results: Low vitamin D levels had been found in most of our patients where 37.3% of cases were vitamin D deficient and 38.2% of cases were vitamin D insufficient while only 24.5 % of cases were vitamin D sufficient. High Pediatric logistic organ dysfunction (PELOD) score and high alkaline phosphatise (ALP) were associated with 25(OH)D deficiency while summer season and sun exposure were protective. There was no significant difference according to vitamin D level as regards PICU stay, patient mortality, presence of sepsis or septic shock and main affected system on admission. Conclusion: We found a high rate of vitamin D deficiency in critically ill children and vitamin D level was negatively correlated with PELOD score. We recommend screening of critically ill children for vitamin D deficiency to restore their serum levels.
Authors and Affiliations
Amina SdqyAl Halwany
Keywords
Related Articles
- EP ID EP285017
- DOI -
- Views 60
- Downloads 0
Quality of Life in Rheumatoid Arthritis patients taking combination DMARDs
Objective: To assess the QOL of RA patients taking non biological combination DMARDs Material & Methods Study Design: Open Label Study Treatment naïve or chronic cases of RA in age group of 18-60 years of both sex with R...
A Comparative Study for Control of Shivering with Clonidine, Butorphanol and Tramadol in Patients Undergoing Neuraxial Blockad
Background: Shivering is a typical issue amid neuraxial anesthesia. This investigation intended to assess the relative adequacy of intravenously directed clonidine, butorphanol and tramadol for control of intraoperative...
Incidence of Amebiasis Among Bloody Diarrhea And Malnutrition Patients With Relation To Gamma Interferon Bellow Five Years of Age in Babylon Province In Iraq
Malnutrition is an underlying factor in many diseases in both children and adults, it increases the incidence of infection including bloody diarrhea (parasite infection mostly Entamoeba histolytica) and potentiates the s...
Glycemic Profile in Chronic Liver Disease
Liver has a pivotal role in glucose homeostasis and maintaining blood glucose values within strict normal limits. Chronic liver disease results in impaired glucose tolerance and diabetes, resulting in the entity called H...
Blindness among Drivers in University of Maiduguri
Background: Although the causes of Road Traffic Accidents are multifactorial, good vision is an important component of safe driving. Objective: The objective of the study was to determine the visual status of motor vehic...