Study of Thyroid dysfunction in pregnancy at Government Maternity Hospital, Osmania Medical College, Hyderabad
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Aim: To study the prevalence of thyroid dysfunction in antenatal women attending antenatal OPD.The association of thyroid dysfunction in relation to: Demographic profile, parity, gestational age, maternal weight and maternal medical disorders like diabetes mellitus on thyroid dysfunction. Background: Thyroid disorders are the second most common endocrinal disorders in pregnancy. Overt hypothyroidism is seen in 0.3-0.5% of the pregnancies. Sub-clinical hypothyroidism is seen in 2-3% of the pregnant women. Hyperthyroidism is seen in 0.1-0.4% of the pregnant women. It has long been recognized that maternal thyroid hormone excess or deficiency can influence the outcome for mother and fetus at all stages of pregnancy. Material and methods: 200 antenatal women attending antenatal OPD at GMH, Osmania medical college, Hyderabad in June and July 2018 for two months are selected randomly irrespective of parity and gestational age, for screening of thyroid dysfunction by TSH estimation. The study also includes cases of known thyroid dysfunction. Results: In 33 women TSH levels are abnormal.TSH levels are <0.3 µIU/ml in 3 women indicating hyperthyroidism. One of these woman was diagnosed before pregnancy.TSH level is >3.5 µIU/ml in 30 women showing hypothyroidism. 9/30 were diagnosed before pregnancy and are on thyroid replacement therapy.21 antenatal women screened are diagnosed during the present pregnancy. 2 of them had overt hypothyroidism with serum TSH >10 µIU/ml. All the women are started on thyroid replacement therapy on the advice of endocrinologist. None of the women with abnormal TSH levels detected in this pregnancy has family history of thyroid dysfunction. Blood sugar levels are normal in all of the 33 women with abnormal serum TSH values. The common associated complication was anemia; pre-eclampsia was noted in one woman. Five out of the 33 women had weight more than 70kg. Conclusion: As the incidence of thyroid dysfunctions is increasing in the women of reproductive age group, even in the iodine sufficient areas, screening for thyroid dysfunction in pregnancy is advisable. It is preferable to do the screening in the 1st Trimester or at the 1st antenatal visit.
Authors and Affiliations
Dr A. Padmaja, Dr V. Lakshmi Sravanthi
Keywords
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- EP ID EP409184
- DOI 10.9790/0853-1711032834.
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