Study on Thyroid Profile In RDS
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
Respiratory Distress syndrome(RDS) in newborn is defined as the presence of any two of the following features:1. Respiratory rate >60. 2.Subcostal/Intercostal retractions. 3.Expiratory grunt/Groaning.In addition, presence of nasal flaring, suprasternalretractions,decreased air entry on auscultation of chest wall will also indicate the presence of respiratory distress. An infant who has an advanced degree of respiratory distress may exhibit additional signssuch as cyanosis,gasping,choking,apnea,stridor.It is more common in early and late pre-term babies.Thyroid function including total T3,T4,TSH were studied in these patients.50 premature new-born with respiratory distress syndrome(RDS),40 prematures comparable by gestational age who failed to develop RDS and 20 full term normal babies.The group of premature newborn infants in whom RDS occurred as compared to other two groups had significantly lower mean total T3,T4 level when matched by gestational age,the difference were also significant.Two days following delivery,the total serum T3,T4 level in the surviving prematures with RDS as compared with prematures without RDS was significantly lower. The mean value for Total T3,T4 and TSH in the respective mothers of the three groups were not significantly different.Since L-thyroxinehas been shown to increase the production of lung surfactant, widely accepted as deficient in RDS newborn infants, an association between lung immaturity and fetal thyroid function postulated.
Authors and Affiliations
Dr. Antony Kisk, Dr. Kiran Kumar M. N, Dr. Deepak Chaturvedi, Dr. M R Akhouri
Keywords
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- EP ID EP594908
- DOI 10.9790/0853-1604075356.
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