Study the Effects of Lead on Thyroid Functions in Alexandria Occupationally Exposed Workers
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 2
Abstract
This study aimed to explore the effects of lead on the thyroid function of Alexandria occupationally exposed workers. One hundred male workers occupationally exposed to lead in a factory for bullets and shots were investigated. The level of blood lead was measured by atomic absorption spectro photometry .Thyroidstimulating hormone, free thyroxine, free triiodothyronune and anti thyroid peroxidase in serum were estimated by enzyme immunoassay. Thyroid ultrasound was performed by an expert radiologist using 5- 10HZ probe device. The workers with higher level of blood lead (40-60 micrograms/dl) showed high Thyroid-stimulating hormone level (0.81 – 9.30 mIU/ml) and abnormal ultrasound findings; volume and echo texture changes. No changes in free thyroxine, free triiodothyronune and anti thyroid peroxidase were observed. We concluded that higher level of blood lead may cause certain damage to thyroid function leading to subclinical hypothyroidism, with no evidence of thyroid immune dysfunction.
Authors and Affiliations
Aliaa Ali Elaghoury
Keywords
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