Study Title: Analysis of Biofilm Formation and Drug Resistance Profile From Sclero-Corneal wounds of The Patients Undergoing Cataract Surgery
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 4
Abstract
The study was aimed to assess the micro flora of sclero-corneal wounds at the end of cataract surgery before application of intra-cameral antibiotic and determine the biofilm forming ability and antimicrobial susceptibility of the isolates obtained. Thisprospective clinical study included 50 patients undergoing manual small incision cataract surgery without any complications, over a period of 6 months. In sterile environment, taking aseptic precautions wipe samples were taken from the surface of bulbar conjunctiva, corneal and scleral corneal incision following uneventful surgery. All samples were plated on various media. Positive growth was obtained from culture of 22 patients and total organisms isolated were 28. Staphylococcus aureus was the most common organism (28.6%) followed by Coagulase negative staphylococcus (14.3%) and Klebsiella pneumoniae (14.3%). 15 of the isolates were weakly, 5 were moderate and 3 were strongly positive biofilm formers. 35.7 % of the isolates were pan-drug resistant. There was a significant correlation between diabetic and positive culture growths (p=0.0118). Multiple factors can lead to post- surgical endophthalmitis with considerable local variation in the causative organisms and the antibiotic susceptibility. All these aspects should be kept in mind to avoid the infection.
Authors and Affiliations
Dr. Lalitha K Raju, Dr. Shalini, Dr. Leela R
Keywords
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- EP ID EP593457
- DOI 10.9790/0853-1604027479.
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