‘Sunshine vitamin deficiency’ – A myth or a fact?
Journal Title: International Journal of Clinical Biochemistry and Research - Year 2018, Vol 5, Issue 1
Abstract
As we live in a country with abundant sunshine the prevalence of this sunshine vitamin deficiency is around 70-100%. Minimum thirty minutes of UV B ray exposure causes the production of 600-1000IU of vitamin D in our body. The cut off values for 25-OH vitamin D deficiency is<20ng/ml. The exact cut off value for ‘deficiency’ and ‘insufficiency’ and its vitamin D therapy in India remains controversial. Despite the controversy the Clinicians often prescribe high dose vitamin D to treat the deficiency. Objectives of the study: To compare the vitamin D levels in apparently healthy office workers and manual laborers. Methods and Materials: This study was conducted on 50 apparently healthy office workers, working indoors from 9am to 5 pm and 50 apparently healthy manual labourers working outdoors, during the month of January and February in Mangalore, India. Results: The mean vitamin D levels were significantly higher (p <0.001) in manual labourers than the office workers (18.14 ± 6.98 and 11.16 ± 7.48). The vitamin D status among the office workers showed 2% having a normal vitamin D level(>30 ng/ml),12% having insufficiency(20 -30ng/ml), 28% having deficiency (<20ng/ml) and 58% having severe deficiency(<10ng/ml) similarly in the manual labourers 4% had normal vitamin D level,28% insufficiency,58% deficiency and 10% having severe deficiency. The hours of exposure and vitamin D concentration had significant correlation (p<0.001). Conclusion: Though there was a positive correlation between the vitamin D levels and the hours of exposure, even then only 4% of the manual labourers were having a normal vitamin D level, hence we conclude by saying that either the hours of exposure to sunlight should be more than 5hrs or a new reference range of vitamin D must be established in our Indian population as majority of our study population were asymptomatic, which could also curb the unnecessary intake of the vitamin D drug.
Authors and Affiliations
Tirthal Rai, Srinidhi Rai, Dr. Janice, P. Kathyayani
Biochemical markers of renal and hepatic function in gestational diabetes mellitus
Aim: To assess the biochemical parameters of renal and hepatic function in women with GDM and compare the results with those of normal pregnant women. Materials and Methods: Cases: The study group consisted of 45women wi...
Speculation of diabetic nephropathy by pro-inflammatory cytokines (IL-6, IL-10) & renal biomolecules
Introduction: Type 2 diabetic nephropathy (T2DN) develops inflammation in kidney which leads to failure. Study designed to evaluate risk of diabetic nephropathy (DN) by inflammatory gene expressions (IL6, IL10) and renal...
Influence of maternal nutrition status during pregnancy on developmental outcome in first 30 days of independent neonatal life
Introduction: Birth weight is an important determinant of infant mortality. Two third of all deaths occurring in first twenty eight days of life happen due to low birth weight. LBW infants suffer higher risk of health co...
Association of serum amylase with insufficient insulin action in Type I and Type II Diabetes Mellitus and Metabolic syndrome
Background: Metabolic syndrome (MetS) and Diabetes mellitus (type I and type II) are emerging as epidemics among non communicable diseases. A lot of research has been done on hyperglycemia in Diabetes mellitus and Metabo...
Performance verification and sigma metrics of creatinine assays
Introduction: Creatinine enzymatic method is more accurate but its own higher cost is the main reason why the use of Jaffe assays is still in practice. The verification step is performed because assay procedure confirms...