Surveillance of tuberculosis co-infection among HIV infected patients and their CD4+ cell count profile
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2015, Vol 5, Issue 3
Abstract
Objective: To determine the occurrence of tuberculosis (TB) among HIV infected patients and their CD4+ cell count profile. Methods: A total of 263 HIV-seropositive patients either hospitalized or reporting to the antiretroviral therapy centre for follow up were included in the study. HIV-seropositive patients were then investigated clinically, radiologically and microbiologically for diagnosis of pulmonary TB as per the revised guidelines issued by WHO. Two early morning sputum samples were collected from patients, and isolation and identification of Mycobacterium tuberculosis was done as per standard protocol. Results: Out of them 41 (15.6%) were TB positive and 222 (84.4%) were TB negative. Among TB positive patients, smear positive and culture positive patients were 19 (7.2%), while smear negative and culture positive were 9 (3.4%). Mean CD4+ T cell counts for HIV-seropositive and HIV-related TB patients were 156.14 cells/µL and 197.24 cells/µL respectively. Conclusions: The clinical manifestations in HIV-related TB patients are quite variable and lead to difficulties in diagnosis. Thus radiological evaluation along with proper laboratory investigation in all clinically suspected cases of tuberculosis is the key for prompt diagnosis and treatment.
Antioxidant and antidiabetic activities of the seed and leaf extracts of Chrysophyllum albidum
Objective: To investigate the antioxidant and antidiabetic activities of the seed and leaf extracts of Chrysophyllum albidum (C. albidum). Methods: After assessing the in vitro ferric reducing power and hydrogen peroxide...
A novel porcine cell culture based protocol for the propagation of hepatitis E virus
Objective: To present a comprehensive protocol for the processing of hepatitis E virus (HEV) infected samples and propagation of the virus in primary cell cultures. Methods: Hepatitis E was extracted from porcine liver a...
Phenolic profiing of Rorippa palustris (L.) Besser (Brassicaceae) by LC-ESI-MS: Chemosystematic signifiance and cytotoxic activity
Objective: To investigate the phenolic profile of Rorippa palustris (R. palustris) compared to Egyptian Rorippa species to evaluate their chemosystematic significance as well as screen cytotoxicity of R. palustris extrac...
In vitro drug susceptibility pattern of Mycobacterium tuberculosis in CAT I and CAT II pulmonary tuberculosis patients in Aligarh, Uttar Pradesh, India
Objective: To evaluate in vitro resistance pattern of the first line anti-tubercular drugs in new and previously treated cases of pulmonary tuberculosis patients in Aligarh region. Methods: This study was carried out inv...
Molecular characterization of vancomycin-intermediate Staphylococcus aureus isolates from Tehran
Objective: To determine the prevalence and some genetic characteristics of clinical isolates of Staphylococcus aureus (S. aureus) with reduced susceptibility to vancomycin. Methods: A total of 414 isolates of S. aureus w...