SURVIVAL OF OPERATED PATIENTS WITH METACHRONOUS AND SYNCHRONOUS LIVER METASTASES FROM COLORECTAL CANCERS
Journal Title: Българско списание за обществено здраве (Bulgarian Journal of Public Health) - Year 2014, Vol 0, Issue 2
Abstract
The study covered 180 patients with metastatic colorectal cancer - 79 with metachronous and 101 with synchronous metastases. The results revealed no significant difference in the survival of the operated individuals with metachronous and synchronous metastases. No significant influence of the factors related to the characteristics of the tumor on survival in both groups was found. The multivariable analysis showed that the number, size, distribution and type of metachronous and synchronous metastases as well as the liver resection type had significant impact on survival and the ranking of the factors in the models was close. Despite the presence of factors associated with poor prognosis for patients with synchronous and metachronous CRLM, aggressive surgery and chemotherapy behavior favorably influenced the survival of patients with advanced colorectal cancer.
Authors and Affiliations
Ivan Vasilevski, Ivelin Takorov, Vasil Mihailov, Evelina Odiseeva, Nikola Vladov
Keywords
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