Survival rate and complications after different types of pelvic exenteration for gynecological cancer

Journal Title: European Journal of Gynaecological Oncology - Year 2019, Vol 40, Issue 1

Abstract

Pelvic exenteration (PE) is an operative method for one-moment removal of pelvic organs, including reproductive tract, bladder, and rectosidgmoid. It is most commonly indicated in gynecologic oncology for treatment of locally advanced cancer or recurrence with central localization. The purpose of this study was to evaluate survival rate and complications in different types of PEs performed for cervical, uterine, and ovarian cancer and to report the authors’ experience. Patients undergoing PE for cervical, uterine, and ovarian cancer (n=46) were prospectively collected. Operative techniques types included total PE (n=9), anterior PE (n=14), posterior PE (n=7), and modified posterior PE (n=16). Overall intra- and postoperative complication rate was 34.8% for the series. Mild complications occurred in 28.2% and severe complications in 6.5%. Perioperative mortality was 2.2%. PE in patients with advanced stage of gynecological malignancies was associated with high complication rate and high perioperative mortality and morbidity. Therefore, operative techniques with proven safety should be used. Creating ureter anastomosis with incontinent urinary conduit from terminal ileum can be considered as such technique. Although all factors that impact negative on quality of life, PE remains an alternative for extending life of these types of patients

Authors and Affiliations

K. Nedyalkov, N. Magunska, B. Bechev, I. Kostov

Keywords

Related Articles

Surgical management of recurrent gynecological cancer: Complete resection is the key to longer survival

Summary Purpose of investigation: This study was conducted to elucidate the efficacy and feasibility of surgical management of recurrent gynecological (cervical, endometrial, and ovarian) cancers. Materials and Methods:...

Expression of FOXA1 in breast cancer and the significance

Objective: The aim of this study to examine the expression of FOXA1, ER, and PR in breast cancer and investigate the association between FOXA1 expression and clinical parameters. Materials and Methods: One hundred one ca...

Cytoreductive surgery combined with HIPEC in newly diagnosed and recurrent ovarian cancer

Objective: Perioperative intraperitoneal chemotherapy after cytoreductive surgery is used in ovarian cancer treatment. The purpose of the study is the evaluation of the effect of hyperthermic intraoperative intraperitone...

Clinical features and prognostic factors associated with malignant transformation of ovarian mature cystic teratoma

Purpose: To explore the clinical characteristics and identify potential prognostic factors associated with malignant transformation (MT) of ovarian mature cystic teratoma (MCT). Materials and Methods: This study analyzed...

The role of erythropoietin and erythropoietin receptor expression in breast cancer

Erythropoietin (EPO) plays a number of important functions in the body. Contrary to original beliefs, its activity is not limited to exerting effects on cells along the erythropoietic pathway. Newly published results con...

Download PDF file
  • EP ID EP663029
  • DOI 10.12892/ejgo4285.2019
  • Views 68
  • Downloads 0

How To Cite

K. Nedyalkov, N. Magunska, B. Bechev, I. Kostov (2019). Survival rate and complications after different types of pelvic exenteration for gynecological cancer. European Journal of Gynaecological Oncology, 40(1), 69-73. https://europub.co.uk./articles/-A-663029