Susceptibility Pattern of Various Azoles Against Candida Species Causing Vulvovaginal Candidiasis
Journal Title: Journal of Medical Research and Practice - Year 2017, Vol 6, Issue 2
Abstract
ABSTRACT ABSTRACT Objective Vulvovaginal candidiasis (VVC) is a common gynecological infection. Although there are many effective antifungal drugs used as topical and systemic therapy, resistance to them is not uncommon. This study aims at identifying the causative species and determining their susceptibility to different azoles. Methods A total of 350 female patients with clinical features of VVC were included. Specimens after culture were identified and subjected to susceptibility testing against various azoles by the disk-diffusion method. Results VVC was detected in 20.5% cases. The commonest infecting species was Candida albicans (81.5%). Candida glabrata was the commonest among non-albican species (57%). Susceptibility testing reveals 91% susceptibility against C. albicans. Non-albicans offer resistance against azoles. Conclusion C. albicans was the major infecting species and fluconazole can be used as an empirical therapy in VVC. In recurrent cases, non-azoles must be used.
Authors and Affiliations
Ranjita Ghadei
Keywords
Related Articles
- EP ID EP185887
- DOI -
- Views 118
- Downloads 0
G6PD deficiency and Thalassemia: Is there any correlation? An institutional study from Northern India
Introduction Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an inherited red blood cell (RBC) enzyme disease, affecting 10% of the world population. It is an X-linked disorder transmitted by gene of intermediate...
A Histopathological Review of Nephrectomy Specimens Received in a Referral Center in South Tamil Nadu
Objectives Simple and radical nephrectomies are done for benign and malignant lesions of the kidney respectively. This study was conducted to find out the histopathological spectrum of diseases that were encountered in t...
Study the Correlation between Dyslipidemia and essential Hypertension in Patients of 20-60 Year Age Group of Vidarbha (Maharashtra), India
This study aims to study the abnormalities of lipid profile and their correlation in hypertensive patients. It was a case control study carried out over a period of 1 year at tertiary care hospital in department of medic...
Use of Autologous Adipose-derived Stromal Vascular Fraction Grafting in Treatment of Knee Osteoarthritis: A Safety and Efficacy Study
Autologous adipose-derived stromal vascular fraction (SVF) grafting done in a single surgical sitting was used to treat 201 osteoarthritic knees of grades II or III (as per Kellgren and Lawrence classification scale) und...
Effect of Topical Application of Omega-3 Fatty Acids in the Treatment of Chronic Gingivitis: A Clinical Study
Aim The effect of topical application of the omega-3 fatty acid gels has been evaluated as an adjunct to scaling over a period of 4 weeks in patients with chronic gingivitis. Materials and Methods The present study was a...