Synthesis and Biological Evaluation of Novel 5,8-Dibromo-2-N-substituted-1,4-Naphthoquinone Derivatives as Potential Antimicrobial Agents
Journal Title: Cumhuriyet Science journal - Year 2018, Vol 39, Issue 3
Abstract
The seven 5,8-dibromo-2-N-substituted-1,4-naphthoquinone derivatives have been synthesized and tested for their in vitro antimicrobial activities. The results suggest that the synthesized 2-N-substituted-1,4-naphthoquinones have high antimicrobial activity. The diffusion capacities of the compounds are also important for the determination of the antimicrobial activities; 2c, 2f and 2g have been shown to be promising compounds for future studies.
Authors and Affiliations
Kıymet BERKİL AKAR, Eda MERCAN, Barış ERAN, Bilge Hilal ÇADIRCI
Keywords
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