SYNTHESIS AND EVALUATION OF SOME NEW 6-FLURO-QUINOLIN-4 (1H)-ONE DERIVATVES FOR THEIR ANTI-MICROBIAL ACTIVITIES
Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2009, Vol 1, Issue 4
Abstract
The present work is a bonafide and novel for the synthesis of 6-fluro-quinolin-4(1H)-one derivatives. Around 30 new derivatives were synthesized, with the standard chemicals and well established procedures. The synthesized compounds were tested for their preliminary tests, physical constants, TLC, solubility, etc. IR, 1H-NMR Spectra and CHN analysis confirmed the structures of the final compounds. The proposed compounds were screened for their antimicrobial, antifungal, antitubercular and anti-inflammatory activities with the standard drugs in the well-equipped microbiology and pharmacology lab by using standard methods.
Authors and Affiliations
Shashikant . R . Pattan , Nachiket S Dighe , C K Hariprasad ,Jayshari S Pattan , Arati V Daithankar , Vinayak M Gaware , Mangesh B Hole
Keywords
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