Synthesis and microbial screening of 6-pyridin-4-yl-2, 3-dihydro-1Hpyridazin- 4-one derivatives
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2013, Vol 1, Issue 3
Abstract
6-pyridin-4-yl-2, 3-dihydro-1H-pyridazin-4-one derivatives were synthesized by a simple method. The isonicotinic acid hydrazide was made to react with acetaldehyde and acetone. This results into the formation of the respective hydrazones. These hydrazones formed were cyclized to the pyridazine derivatives. All synthesized compounds were subjected to antimicrobial activity.
Authors and Affiliations
Athar Javed| Govt. College of Pharmacy, Rohru, Shimla, H. P. India, M. S. Bhatia| Bharti Vidyapeeth College of Pharmacy, Kolhapur, Maharashtra, India, Mayuresh Shinde| Bharti Vidyapeeth College of Pharmacy, Kolhapur, Maharashtra, India, Vinod Singh| Gurukul Kangri University, Uttarakhand, India
Keywords
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