Synthesis, crystal structure and antifungal activity of dihydroisoquinoline Oxaziridines Substitued in Position 1
Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2014, Vol 10, Issue 4
Abstract
We report here the synthesis and the X-ray crystallography of dihydroisoquinoline oxaziridines with methyl substitute in position 1 and with nitro group in position 7 (compound 3b). We also synthesized the compound 3a without nitro. These compounds have been prepared by the peracidic oxidation of imines with m-chloroperbenzoic (m-CPBA) like oxidizing agent. This two compounds exhibit higher antifungal activity.
Authors and Affiliations
Mouna Bouzid, Raed Abdennabi, Chakib Hrizi, Neji Gharsallah, Majed Kammoun
Keywords
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- EP ID EP652717
- DOI 10.24297/jac.v10i4.893
- Views 153
- Downloads 0
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