Synthesis of Carbethoxycinnoline Derivatives and Antimicrobial Evaluation
Journal Title: Journal of Biological and chemical Chronicles - Year 2018, Vol 4, Issue 2
Abstract
3-Carbethoxy-6-substituted-4-methylcinnolines have been synthesized by cyclization of phenylhydrazonocarbethoxyacetones under microwave irradiations using polyphosphoric acid as condensing agent. The phenylhydrazonocarbethoxyacetones are prepared from benzenediazonium chloride and ethylacetoacetate. The antibacterial potential of the title compounds has been described against different bacteria’s.
Authors and Affiliations
Komal Jakhar
Keywords
Related Articles
- EP ID EP626892
- DOI -
- Views 172
- Downloads 0
Synthesis of Resorufin Based Chromogenic and Fluorescent Probe for Detection of Mercury
Mercury in its lipophilic and inorganic form is a major threat to the environment and to human health. It is therefore highly necessary to develop a chemosensor for mercury detection. A novel fluorescent probe for mercur...
Apparent Molar Volume and Expansibility Behaviour of Magnesium, Calcium and Strontium caprate in Non-aqueous Medium
The density measurements, of magnesium, calcium and strontium caprate in non - aqueous medium at different temperatures (25-40º C) has been used to evaluate various significant parameters viz. apparent molar volume (v...
Ferrous Sulphate Catalysed Synthesis of 1, 5-Benzothiazepines using Sonication Method
One step synthesis of various aromatic substituted, 1-5-benzothiazepines carried by the reaction of different substituted chalcone with ortho-aminothiophenol in sonication at 40ºC using ferrous sulphate as catalyst. This...
Novel Analytical Method Development and Validation for Estimation of Clinical Important Rosuvastatin in Bulk and Pharmaceutical Dosage Form by UV Spectroscopy Method Using Phosphate Buffer Solubility
Biosynthesis of cholesterol is a natural phenomenon and gets completed in lever in 25 steps. Disorder in any of the steps may cause over or under production of cholesterol that may lead ultimately to atherosclerosis, thr...
Isolation and Characterisation on Proteus vulgaris from Mangrove Sediment of Vellar Estuary for Urease Production
Urease is a virulence factor found in various pathogenic bacteria. It is essential in colonization of a host organism and in maintenance of bacterial cells in tissues. Due to its enzymatic activity, urease has a toxic ef...