Synthesis of icosadeuterio-benzopinacol (Benzopinacol-d20)
Journal Title: Journal of Medicinal and Chemical Sciences - Year 2020, Vol 3, Issue 0
Abstract
This work reports on synthesis of high yield (92%) of isosadeuterio-benzopinacol (benzopinacol-d20) via photo-reductive dimerization of benzophenone-d10. The latter compound was obtained using an improved method to achieve a material with high isotopic purity (> 99%). This material can be served for calibration of mass spectrometric assays. In this study, it was also observed that benzophenone-d10 reacts faster than its natural abundance counterpart. However, elucidating the origin of this phenomenon will require additional work.
Authors and Affiliations
Steeve M. Adjibodé, Urbain C. Kasséhin, Fernand A. Gbaguidi, Jacques H. Poupaert
Keywords
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- EP ID EP608515
- DOI 10.26655/JMCHEMSCI.2020.1.4
- Views 132
- Downloads 0
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