Synthesis, spectral studies and antimicrobial activity of a new hexahydrotriazine compound
Journal Title: Journal of New technology and Materials - Year 2017, Vol 7, Issue 2
Abstract
An unsymmetrical original structure of 1.3- bis( 2-bromophenyl)-5-isopropyl-1.3.5-Triazacyclohexane was synthesized via a long one-step mixed condensation reaction of 2:1stoichiometric ratio, 2-bromoaniline and isopropylamine with formalin. The desired novel compoundwas obtained as colorless needles in good yield of 71%. The Characterization of the synthesized compound has been done by different spectroscopic methods like FT-IR, 1H NMR ,13C NMR, UV , and elementary analysis. In this research work, we tested the antimicrobial activity of this new product where we used Gram‐positive and Gram‐negative bacteria by the diffusion method on agar medium.
Authors and Affiliations
Souhila Malki, Leila Lefrada, Wissam Mazouz, Valérie Hardouin Duparc, Frank Schaper, Ahcene Bouchemma, Meriem Hadjem, Mustapha Bouhenguel
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