Systematic analysis of components and contents in Houttuynia cordata Thunb
Journal Title: Traditional Medicine Research - Year 2017, Vol 2, Issue 4
Abstract
Objective: This study aims to provide the material basis for the molecular mechanism of Yuxingcao (Houttuynia cordata Thunb, HCT) through the method of evidence-based study to summarize the natural constituents isolated from HCT. Methods: We searched CNKI, Wanfang, VIP, Pubmed and relevant conference compilations. The keywords were “Yuxingcao or Houttuynia cordata Thunb” and “components” or “ingredients” or “constituent” or “volatile oil” or “flavonoids” or “terpene” or “content”, both in Chinese and English. According to the inclusion and exclusion criteria, the reported compositions and contents have been summarized, and SPSS software was used to draw the boxplot of contents. Results: A total of 603 natural compounds in 11 categories were obtained from pooled articles. In the diverse components, the number of aliphatic compounds (n = 259) and terpenoids (n = 158) are more than those of flavonoids (n = 26), alkaloids (n = 42) and aromatics (n = 42). While, in the part of volatile oils of HCT, the largest components are aliphatic compounds (mainly distributed on the ground) and terpenoids (mainly distributed in the underground). Although, methyl n-nonylketone is distributed in the whole herb plant, a large proportion is present in the underground parts. As for non-volatiles, the flavonoid content (mainly distributed on the ground) was the highest, among which quercetin and its glycosyl derivatives were the prominent. Conclusion: The results of this study provide a more comprehensive material basis for the further study of HCT. It is also helpful to explain the mechanisms of anti-oxidant, anti-inflammatory, anti-bacterial, anti-viral and anti-cancer effects from the molecular target and molecular network levels.
Authors and Affiliations
Dong Xin-Yi, Jin Yi, Yang Li-Ping
Keywords
Related Articles
- EP ID EP45252
- DOI 10.12032/TMR201708053
- Views 262
- Downloads 0
A Literature Review of the Acupoint Plaster Therapy for Asthma in Summer
Treating winter diseases in summer is characterized by warming Yang, which is recuperating in summer, to treat some chronic diseases commonly seen in winter. This treatment belongs to the chronomedicine of Traditional Ch...
Is "Pangolin (Manis Squama) is not used in medicine" an improvement in the protection of precious and rare species or an improvement in the safety of using medicine?
Recently, a number of reports about pangolin have become hot news: The Chinese Pharmacopoeia (2020 edition) has not continued to include the drug-using standards for pangolin (Manis Squama), aristolochic (Aristolochia...
A broad perspective on COVID-19: a global pandemic and a focus on preventive medicine
Coronavirus 2019 has become a highly infectious disease caused by severe acute respiratory syndrome coronavirus-2, a strain of novel coronavirus, which challenges millions of global healthcare facilities. Coronavirus are...
Research on Xijiao Dihuang Decoction suppressing platelet apoptosis in immune-mediated aplastic anemia based on mitochondrial mediated pathway
The aplastic anemia mice model was established in this study. BALB/c mice shall be treated with whole body irradiation with 60 Co-γradiation (5.5Gy, 1.1Gy/min × 5 min). then within 4 h, DBA/2 mice were injected lymphocyt...
A systematical review of traditional Ayurvedic and morden medical perspectives on Ghrita (clarified butter): a boon or bane
Highlights Ghrita (clarified butter), treated as the culprit of a number of diseases, has been depicted incorrectly for a long time. This review presents the complete picture in view of Ayurvedic perspective and recen...