TABLET GRANULATION: CURRENT SCENARIO AND RECENT ADVANCES
Journal Title: Universal Journal of Pharmaceutical Research - Year 2017, Vol 2, Issue 5
Abstract
Granulation is a size enlargement process, in fine or coarse particles converted into physically stronger and larger agglomerates having good flow property, better compression characteristics and uniformity, prevent segregation of the blend components, improve content uniformity, and eliminate excessive amounts of fine particles. Size of granules has a size range of 0.2 to 4.0 mm, depending on their subsequent use. Size of the granules depends on the quantity and feeding rate of granulating liquid. The selection of process to prepare granules requires thorough knowledge of physicochemical properties of the drug, excipients, required flow and release properties, to name a few. At current scenario available technologies includes, spray drying, roller compaction, high shear mixing, and fluid bed granulation etc. The objective of present work is to focus on the commonly used and novel granulation technologies like such as pneumatic dry granulation, steam granulation, moisture-activated dry granulation, thermal adhesion granulation, freeze granulation, and foamed binder or foam granulation.
Authors and Affiliations
Bipin Kumar Verma, Savita Pandey, Priti Arya
Keywords
Related Articles
- EP ID EP36415
- DOI https://doi.org/10.22270/ujpr.v2i5.RW1
- Views 295
- Downloads 0
Editorial...
With an immense sense of approbation and unalloyed concession, I appreciate my appointment as an editorial board member of Universal Journal of Pharmaceutical Research (UJPR). My sincere and heart-felt congratulation to...
LIQUISOLID TECHNIQUE FOR DISSOLUTION AND BIOAVAILABILITY ENHANCEMENT OF POORLY SOLUBLE DRUGS
Liquisolid formulations have attracted substantial interest as an efficient means of improving the dissolution and ultimately bioavailability. The technique is based upon the admixture of drug loaded solutions with appro...
THE ASSOCIATION OF ADULT MALE AND FEMALE INFERTILITY WITH CELIAC DISEASE PATIENTS IN YEMEN
Celiac disease’s potentially destructive effect on reproductive health is among the most vital matters associated with progress awareness. Men and women with unexplained infertility, women with recurrent abortions, intra...
AN UPDATED REVIEW ON TRANSFERSOMES: A NOVEL VESICULAR SYSTEM FOR TRANSDERMAL DRUG DELIVERY
Transdermal route is an interesting option in this respect because a transdermal route is convenient and safe, avoid first pass metabolism, predictable and extended duration of activity, minimizing undesirable side effec...
FAST DISSOLVING DRUG DELIVERY SYSTEMS: FORMULATION, PREPARATION TECHNIQUES AND EVALUATION
The Fast Dissolving Drug Delivery Systems sets a new benchmark was an expansion that came into existence in the early 1980’s and combat over the use of the different dosage form like tablets, suspension, syrups, capsules...