Tamsulosin-induced Hyperprolactinemia in a Patient with Multiple Sclerosis: A Case Report

Journal Title: Journal of Urological Surgery - Year 2019, Vol 6, Issue 2

Abstract

Drug-induced hyperprolactinemia is one of the most common causes of non-physiologic hyperprolactinemia. In contrary to other anterior pituitary hormones, prolactin is not controlled via hypothalamic-pituitary negative feedback mechanism. Since prolactin secretion is inhibited mainly by dopamine, some drugs such as antipsychotics and prokinetics which block dopamine receptors may lead to hyperprolactinemia. Nevertheless, despite this well-known phenomenon, most of cases of drug-induced hyperprolactinemia are asymptomatic. On the other hand, hyperprolactinemia due to tamsulosin that is an alpha adrenergic receptor antagonist has not been reported yet. Herein, we present a 39-year-old woman with multiple sclerosis who developed hyperprolactinemia after starting treatment with tamsulosin for neurogenic bladder disease.

Authors and Affiliations

Ahmet Görgel, Ahmet Soylu, Sacit Görgel, Mehmet Tecellioğlu, Mehmet Sarıer

Keywords

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  • EP ID EP49004
  • DOI 10.4274/jus.galenos.2018.2436
  • Views 332
  • Downloads 0

How To Cite

Ahmet Görgel, Ahmet Soylu, Sacit Görgel, Mehmet Tecellioğlu, Mehmet Sarıer (2019). Tamsulosin-induced Hyperprolactinemia in a Patient with Multiple Sclerosis: A Case Report. Journal of Urological Surgery, 6(2), -. https://europub.co.uk./articles/-A-49004