Terlipressin and Octreotide in Esophageal Varices: A Comparative Study
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Aim: To Compare the role of Terlipressin And Octreotide in Esophageal Varices Methods: 30 Cirrhotic Patients with esophageal variceal bleed were taken into consideration.15 Patients (Group A) were given Terlipressin in the does of 2g bolus i.v every 4 hours first 2 days.The dose is halved after bleeding controlled & maintained up to 5 days and other 15 Patients were given octreotide in the dose of initial IV bolus 50μg followed by a continuous infusion of 50μg per hour .The infusion maintained for 5 days.Two groups were compared for efficacy and safety. Result: Total 30 patients were included in the study.Baseline characteristics of two groups were comparable for age,Hb at presentation,Pulse rate,Systolic and Diastolic B.P.Statistical Analysis was done using unpaired T test. Conclusion: The efficacy of Terlipressin was not inferior to Octreotide as an adjuvant therapy for the control of esophageal variceal bleed.
Authors and Affiliations
Rasmirekha Behera, Sushant Sethi
Keywords
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- EP ID EP593476
- DOI 10.9790/0853-1603039295
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