Tertiary cyclic amides in Vilsmeier type reaction with indoles
Journal Title: Progress in Chemical and Biochemical Research - Year 2019, Vol 2, Issue 1
Abstract
The reaction of indoles with the complex formed from tertiary cyclic amides and phosphorus oxychloride, followed by basification using sodium hydroxide, was studied. In the case of five member amide rings, 3-(1-alkyl-pyrrolidine-2-ylidene)3H-indoles were obtained but in the case of six and seven member amide rings, ring opening was occurred and amino ketones were obtained.
Authors and Affiliations
Masomeh Aghazadeh
Keywords
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- EP ID EP634763
- DOI 10.33945/SAMI/PCBR.2019.2.3439
- Views 73
- Downloads 0
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