Testicular Microlithiasis: Case Report and Literature Review - - - Mikrolitijaza testisa: prikaz slučaja sa osvrtom na literaturu
Journal Title: Acta Facultatis Medicae Naissensis - Year 2017, Vol 34, Issue 3
Abstract
Testicular microlithiasis is a condition characterized by the ultrasonographic findings with multiple micro-liths, with the prevalence of 0.6% to 9%. This is a condition of unknown etiology; however, in many cases it may be associated with cryptorchidism, Klinefelter syndrome, Down syndrome, varicocele, testicular torsion and male pseudohermaphroditism. Many retrospective studies point to the association between testicular microlithiasis and testicular cancer. We report a case of a 50-year-old patient who presented to the urologist because of dysuric symptoms. Ultrasonographic examination of both testicles revealed microcalcifications in large numbers, i.e. "the pheno-menon of the starry sky". More than 20 microcalcifications were present on the cross section of both testicles. Standard laboratory blood tests were normal. Prostate-specific antigen was 1.22 ng/ml. If risk factors for deve-loping cancer are present, some authors recommend a biopsy of the testicles. However, based on the literature review, currently, there is no a strictly defined protocol. - - - Mikrolitijaza testisa je stanje koje se na ultrasonografskom nalazu karakteriše multiplim mikrolitima, sa prevalencijom od 0,6% do 9%. Nejasne je etiologije, ali u velikom broju slučajeva može biti udružena sa kriptorhizmom, Klinefelterovim sindromom, Daunovim sindromom, varikocelom, torzijom testisa i muškim pseudo-hermafroditizmom. Mnoge retrospektivne studije ukazuju na povezanost mikrolitijaze testisa i karcinoma testisa. Prikazujemo slučaj pedesetogodišnjeg bolesnika koji se javlja urologu zbog dizuričnih smetnji. Na ultrasonografskom pregledu u oba testisa se uočavaju mikrokalcifikacije u velikom broju, tzv. “fenomen zvezdanog neba.” Na poprečnom preseku oba testisa uočeno je više od 20 mikrokalcifikacija. Kompletna krvna slika i biohemijske analize bile su u referentnim okvirima. Specifični antigen prostate iznosio je 1,22 ng/ml. Ukoliko postoje faktor irizika za razvoj karcinoma, neki autori preporučuju biopsiju testisa. Međutim, za sada, na osnovu pregleda literature ne postoji jasno utvrđen protokol.
Authors and Affiliations
Goran Savić, Vladimir Vasić, Milan Petrović, Jovan Petrović, Dragoslav Bašić
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