Testosterone and Quality of Women’s Life (Literature Review)
Journal Title: Міжнародний ендокринологічний журнал - Year 2012, Vol 42, Issue 2
Abstract
Sexual desire disorder is a common clinical problem that may have a very negative impact on a woman’s quality of life. Diagnosis and treatment are challenging, as one must keep in mind the complex web of factors influencing sexual functioning alone or in concert. Data suggest that androgens are significant independent factors affecting sexual desire, sexual activity and satisfaction, as well as other components of women’s health. For decades, physicians used various androgen preparations to improve sexual function in women, based on the results of clinical trials and personal clinical observations. Today, there is a great database from randomized placebo-controlled trials that low-dose testosterone treatment is efficacious in women with sexual desire disorder who have an established cause of androgen deficiency such as surgical menopause. Recent data support the hypotheses that androgens may also be beneficial in naturally menopausal women or in premenopausal women with low circulating testosterone levels and a decrease in satisfying sexual activity. No single testosterone level has been found to be predictive for low female sexual function. Long-term safety is not yet established. Several clinical trials are in progress to further investigate potential benefits and risks of androgen treatment in women with sexual dysfunction.
Authors and Affiliations
F. A. Khaidarova, S. S. Nigmatova
Keywords
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