Thalamic medial system is a key link in the neural circuits of negative emotions induced by chronic pain
Journal Title: Journal of Air Force Medical University - Year 2023, Vol 44, Issue 11
Abstract
Chronic pain and its induced negative emotional responses ( fear, anxiety, depression, etc. ) seriously affect the combat effectiveness of troops and the quality of life of patients, but its related neural circuits and mechanisms are unsolved problems in life science. In the central nervous system, the neural pathways for nociceptive sensory information transmission are composed of the thalamic lateral system and the thalamic medial system. The thalamic medial system is primarily relayed in the dorsal thalamic midline and medial nuclei ( TMMN), and it terminates in the limbic cortex and subcortical structures of the cerebrum. In addition to being associated with pain, it is also associated with negative emotional responses. Therefore, in recent years, we have focused on the role of neural circuits formed between TMMN and the cerebral cortex and subcortical structures in chronic pain and its negative emotional responses. The results of these studies not only show that the thalamic medial system is a key link in the neural circuits of negative emotions induced by chronic pain, but also lay a foundation for revealing the underlying mechanism of chronic pain and its induced negative emotional responses, and provide clues for further research.
Authors and Affiliations
LI Yunqing
Keywords
Related Articles
- EP ID EP724138
- DOI -
- Views 37
- Downloads 0
Nonlinear dynamics research of eye-tracking data in MOOC video learning
Objective To explore the nonlinear dynamics characteristics of eye-tracking data in MOOC video learning. Methods In this study, the sliding window permutation entropy of pupil diameter was calculated, and the obtained...
Problems and challenges of heart transplantation and artificial heart in the treatment of end-stage heart failure
The incidence and mortality of heart failure are high, which seriously affects the quality of life and longevity of patients. Allogeneic heart transplantation ( ereinafter referred to as heart transplantation) is an effe...
Correlation between ApoE gene polymorphism, Hcy and coronary heart disease in T2DM patients
Objective To analyze the correlation between apolipoprotein E (ApoE) gene polymorphism, homocysteine (Hcy) level and coronary heart disease ( CHD) in type 2 diabetes mellitus ( T2DM) patients. Methods A total of 134 T2...
Clinical effect analysis of capsule reconstruction under pectoralis major to repair exposed pacemaker
Objective To investigate the clinical effect of capsule reconstruction under pectoralis major to repair exposed pacemaker. Methods From March 2017 to July 2021, 32 patients with exposed pacemakers treated in the Depart...
Expression and clinical significance of SEPHS2 in cutaneous malignant melanoma
Objective To explore the expression and clinical significance of selenophosphoric synthetase 2 (SEPHS2) in cutaneous malignant melanoma (CMM) by bioinformatics methods. Methods The mRNA microarray expression profiles r...