The Effect of 4 Weeks of Flaxseed Extract Supplementation on Serum Concentration of Brain-Derived Neurotrophic Factor and C-Reactive Protein
Journal Title: مجله علمی- پژوهشی دانشگاه علوم پزشکی قم - Year 2017, Vol 10, Issue 11
Abstract
Background and Objective: Omega-3 Supplementation has different effects on the body. Terefore, this study was carried out with the aim of investigating the effect of 4 weeks of flaxseed extract supplementation on serum concentrations of Brain-derived neurotrophic factor (BDNF) and C-reactive protein (CRP). Methods: In this double-blind study, 24 male students (mean age, 23.21±1.98) were randomly divided into two groups, including flaxseed extract (n=12) and placebo (n=12). After 4 weeks of supplementation with flaxseed extract, serum levels of BDNF and CRP was measured in fasting state. BDNF level was measured using an enzyme-linked immunosorbent assay (ELISA) kit, and CRP level was measured using an immunoturbidimetric assay kit. Data were analyzed using t-test. The level of significance was set at p<0.05. Results: After four weeks of supplementation with flaxseed extract the mean serum level of BDNF significantly increased (p<0.001), but no significant change was observed in the serum level of CRP (p<0.591). Conclusion: It seems that supplementation with flaxseed extract through increasing BDNF level is useful for the improvement of cognitive and functional benefits of the brain.
Authors and Affiliations
Hosein Hosein, Eisa Eisa, Zia Zia, Ghsem Ghsem, Shamseddin Shamseddin
Keywords
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