THE EFFECT OF 5 FRACTIONAL EXTRACTS OF ACER TEGMENTOSUM MAXIM. CONCENTRATED IN DECOMPRESSED VACUUM ON DENTAL CARIES-INDUCING BACTERIA
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 1
Abstract
Acer tegmentosum Maxim. (Acer TM) was concentrated in decompressed vacuum to obtain 5 factional extracts, and the amount of dental caries-inducing bacteria and periodontitis-inducing bacteria that were inhibited depending on the concentration of Acer TM was examined. The concentration of proteins contained in Acer TM Fractions 1, 2, 3, 4 and 5 was 200 (mg/mL), 225 (mg/mL), 110 (mg/mL), 150 (mg/mL) and 90 (mg/mL) respectively. The protein concentration of Acer TM Fraction 2 was the highest. The antibacterial effect of each Acer TM fraction on S. mutans was examined, and no antibacterial effect was observed in Fractions 1, 2 and 3. In the extract of Fraction 4, 2mm and 4mm antibacterial zones were observed at 50mg/ml and 100mg/ml respectively. In the extract of Fraction 5, 2mm and 4mm antibacterial zones were observed at 50mg/ml and 100mg/ml respectively. In the case of P. gingivalis, no antibacterial effect was observed in Fractions 1, 2 and 3. In Fraction 4, 1mm, 3mm, 6mm and 8mm antibacterial zones were observed at 10mg/ml, 25mg/ml, 50mg/ml and 100mg/ml respectively. In the extract of Fraction 4, an antibacterial effect was observed across the entire concentration range from the low concentration to the high concentration. In the extract of Fraction 5, 4mm and 10mm antibacterial zones were observed at 50mg/ml and 100mg/ml respectively, showing the highest antibacterial effect. Therefore, the extract of Acer TM Fractions 4 and 5 seems to be used as a candidate natural plant to treat periodontal diseases that induce dental caries-causing bacteria.
Authors and Affiliations
Kyung-Yae Hyun
Keywords
Related Articles
- EP ID EP672403
- DOI -
- Views 143
- Downloads 0
INFLUENCE OF STORAGE CONDITIONS ON PHARMACEUTICAL PROPERTIES OF SOME MARKETED BRANDS OF PARACETAMOL TABLETS AVAILABLE IN TRIPOLI AREA
This work was conducted after reporting a 2 months of poor storage conditions of temperature and humidity in some pharmacies during power outage on summer 2014 which led us to evaluate and compare the influence of differ...
ULTRASONOGRAPHY IN THE MANAGEMENT OF SICKLE CELL ANAEMIA – NEED FOR A SHIFT IN SUB-SAHARAN AFRICA
Sickle cell anaemia is a genetic condition that results in a chronic hemolytic anaemia. This condition is very common in sub-Saharan Africa. It is associated with vaso-occlusive, anaemic and infarctive crises and infecti...
CHEMICAL COMPOSITION AND PHARMACOLOGICAL ACTIVITIES OF ESSENTIAL OILS EXTRACTED FROM “EUCALYPTUS GLOBULUS”
Objective: To compare the chemical composition and the antioxidant capacities of Essential Oil extracted from Lebanese Eucalyptus Globulus leaves and flowers. Materials and Methods: The Essential Oils were extracted by H...
ETHNOBOTANIC INVESTIGATION, DETERMINATION OF PHYSICAL CHARASTERISTICS AND ANTI-NUTRITIONAL FACTORS OF FRUITS OF MYRIANTHUS ABOREUS FROM COTE D’IVOIRE
The aim of this study was the valuation of the underexploited said plants still called " spontaneous plants " through the realization of the ethnobotanic study and the determination of physical Charasteristics and antinu...
ASSOCIATION OF QAT CHEWING AND GINGIVAL RECESSION
Background: Qat chewing is widely practiced by adult population in Jazan region. Both periodontal disease and teeth discoloration are the most common problems reportedly associated with qat chewing. The aims of the prese...