The effect of antibiotic therapy on the incidence of Staphylococcus aureus infections
Journal Title: Ortopedia Traumatologia Rehabilitacja - Year 2007, Vol 9, Issue 5
Abstract
This paper reports on aetiological factors, including mostly S. aureus infections, and antibiotic use in the pretreatment and treatment of complicating infections in patients hospitalised at the Department of Orthopaedics and Musculoskeletal Traumatology, Gdańsk Medical University, between 1995 and 2004.The analysis sought to establish a correlation, via statistical analysis, between the usage of specific antibiotic classes, with special regard to lincosamides, and S. aureus infection rates.The study population included 22,686 patients admitted for elective surgery (accounting for 86.9% to 75.1% of the sample in different years) or with acute injuries.The rate of infections ranged from 2.79% to 1%, decreasing in a statistically significant manner over time. S. aureus was the dominant pathogen, accounting for 67.3% to 27.6% of the total number of bacterial strains. During the time frame of the study, the incidence of osteitis fell considerably, from 0.8% to 0.05% of the total number of patients. This was paralleled by a major increase in the use of lincosamides, mostly clindamycin. The increase in lincosamide use correlated with the decreasing incidence of S. aureus infections.The statistical outcome of this 10-year study has been used to develop schemes of antibiotic therapy in the Department, a necessary component of the Hospital’s economic policy at the moment.A major fall in the incidence of nosocomial infections can be achieved by focussing on adequate antibiotic prophylaxis, pretreatment and appropriate treatment of acute infections.
Authors and Affiliations
Joanna Dzwonkowska , Julianna Kurlenda , Bogusław Baczkowski , Stanisław Mazurkiewicz , Ivelin Uzunov , Włodzimierz Ziółkowski , Agnieszka Markowicz
Keywords
Related Articles
- EP ID EP56760
- DOI -
- Views 99
- Downloads 0
Wyniki leczenia przerzutów raka stercza do kości po zastosowaniu radiochirurgii CyberKnife
Wstęp. Przerzuty raka stercza do kości są często związane z silnymi dolegliwościami bólowymi. Standardowa radioterapia paliatywna nie zapewnia pełnego efektu analgetycznego u większości chorych. Radiochirurgia CyberKnife...
Ipsilateral Combination of Galeazzi and Monteggia fractures in a ten-year-old patient: A Case Report<br />
Galeazzi fractures represent approximately 3 to 6 percent of forearm fractures, whereas Monteggia fractures represent 1 to 2 percent. The combination of these injuries in the same extremity is an exceedingly rare occurre...
Wstępne wyniki bezcementowej całkowitej aloplastyki stawu skokowo-goleniowego
Wstęp. Po wprowadzeniu do powszechnego użycia endoprotez stawu skokowo-goleniowego nowej generacji, alloplastyka całkowita tego stawu stała się alternatywą wobec artrodezy w zaawansowanych zmianach zwyrodnieniowych. Cele...
The effect of clodronate on bone mineral density and serum osteocalcin in postmenopausal women with osteopenia - a prospective, randomized, placebo-controlled study.
Background. The efficacy of bisphosphonates in treatment of established osteoporosis has been well-documented; less data have been published on their efficacy in the prophylaxis of postmenopausal bone loss in women with...
New conservative treatment of idiopathic scoliosis: effectiveness of therapy
Background. This article provides basic information concerning a new conservative treatment for idiopathic scoliosis, with appropriate asymmetric flexion-rotation exercises and special redressing positions. Material and...