THE EFFECT OF DEXAMETHASONE ON POST-OPERATIVE NAUSEA AND VOMITING IN PATIENTS WHO UNDERWENT TONSILLITIS SURGERY AT THE ADESH INSTITUTE OF MEDICAL SCIENCE AND RESEARCH UNIVERSITY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2015, Vol 2, Issue 35
Abstract
PONV occurs frequently after day case tonsillectomy surgery both 5-HT3 antagonists and dexamethasone are superior to placebo in the prophylaxis of PONV in his setting. Our study has compared the efficacy of ondansetron plus dexamethasone with each anti-emetic alone for the prevention of PONV in patients undergoing day case tonsillectomy surgery. Present study was undertaken on 279 patients in the age group of 10-38yrs. Group 1 received Inj. Dexamethasone 8mg as single dose I V bolus 5 minutes before induction of anaesthesia. Group 2 received Inj. Ondansetron 4mg as single dose I V bolus 5 minutes before induction of anaesthesia. Group 3 received Inj. Ondansetron 4mg with Inj. Dexamethasone 8mg as single dose I V bolus 5 minutes before induction of anaesthesia A standard anaesthetic protocol was used in all the patients. As per our observations, the incidence of PONV in 0 – 4 hours postoperative period was statistically significant. The observations were inconclusive beyond the 4 hour period in combination group as well as either drug group. Combination of Inj. Ondansetron 4mg with Inj. Dexamethasone 8mg proved to be more efficacious over either drug alone.
Authors and Affiliations
Grace Budhiraja, Monika Gupta, Paramdeep Singh
Keywords
Related Articles
- EP ID EP231807
- DOI 10.18410/jebmh/2015/746
- Views 84
- Downloads 0
INCIDENCE AND CLINICOPATHOLOGICAL FEATURES OF NEUROCUTANEOUS DISORDERS
BACKGROUND Neurocutaneous disorders are genetically determined disorders showing both cutaneous and neurologic involvement. The definition includes both hereditary and non-hereditary phenotypes, but excludes acquired dis...
WOUND CARE IN BURNS AND ITS OUTCOME
Burn injury is a serious public health Problem in developing countries like India. Study was conducted to know the male female ratio, percentage of born injury according to age and sex distribution, treatment and outcome...
USE OF TWO STEP FOOT-REST UTILIZED FOR MAKING LITHOTOMY POSITION FOR ANORECTO-UROGENITAL SURGERIES IN INFANT PATIENTS WITH EASY APPROACH FOR ANAESTHESIOLOGIST AS WELL AS FOR SURGEON
This study was carried out in 40 infant patients with the aim is to provide optimal position for better surgical access and better access for anaesthesiologist regarding patient’s monitoring while minimizing manpower wit...
A HISTOPATHOLOGICAL STUDY OF PROSTATE LESIONS IN JAMSHEDPUR, JHARKHAND, INDIA
BACKGROUND Cancer of the prostate is typically a disease of men older than age 50 years. It is the most common cancer in west and the 2nd leading cause of cancer death among men. The objective of this study is to evaluat...
OCULAR MANIFESTATIONS OF ATOPIC DERMATITIS- AN OBSERVATIONAL STUDY IN A TERTIARY CARE CENTRE IN WESTERN ODISHA
BACKGROUND Atopic dermatitis (AD) also known as atopic eczema, is an allergic condition with hereditary predisposition. It mostly presents with intensely itchy skin, raised, splotchy lesions anywhere throughout the body....