The Effect of Gold Nanoparticles on Electrical Impedance of Tissue on Low Frequency Ranges
Journal Title: Journal of Biomedical Physics and Engineering - Year 2018, Vol 8, Issue 3
Abstract
Introduction: Electrical impedance of tissues on low frequencies includes useful information about functional and structural changes in tissues. This property is used in Electrical Impedance Tomography (EIT) imaging modality for the detection of lesions in tissues. Objective: The goal of this article is to study changes in electrical impedance of tissues in the presence of gold nanoparticles. Materials and Methods: Spherical gold nanoparticles with size of 20- 25 nm were synthesized with Turkevich method. Size distribution and shape of nanoparticles were characterized by transmission electron microscopy (TEM). Electrical impedance of two types of phantoms (chicken fat and muscle paste tissues) was measured by 4-electrode method with and without gold nanoparticles. Results: Results demonstrate a reduction in electrical impedance of tissues in the presence of gold nanoparticles. However, this reduction is not the same for fat and muscle tissues. Reductions in resistive impedance are 40.24 1.93 Ω Ω and for fat and muscle tissues on the frequency of 1 KHz, respectively. A reduction in electrical impedance is accompanied by a rise in electrical conductance leading to increase in EIT signal. Conclusion: As signal enhancement is different for fat and muscle tissues; presence of gold nanoparticles could be used to improve EIT image contrast.
Authors and Affiliations
M. Ostovari, N. Riahi Alam, M. M. Gharibvand
Keywords
Related Articles
- EP ID EP455524
- DOI -
- Views 100
- Downloads 0
Cancers of the Brain and CNS: Global Patterns and Trends in Incidence
Miranda-Filho et al. in their recently published paper entitled “Cancers of the brain and CNS: global patterns and trends in incidence” provided a global status report of the geographic and temporal variations in the inc...
A Monte Carlo Study on Dose Enhancement by Homogeneous and Inhomogeneous Distributions of Gold Nanoparticles in Radiotherapy with Low Energy X-rays
Background: To enhance the dose to tumor, the use of high atomic number elements has been proposed. Objective: The aim of this study is to investigate the effect of gold nanoparticle distribution on dose enhancement in t...
Diagnosis of OCD Patients Using Drawing Features of Bender Gestalt Shapes
Background: Since psychological tests such as questionnaire or drawing tests are almost qualitative, their results carry a degree of uncertainty and sometimes subjectivity. The deficiency of all drawing test is that the...
Combined Effect of Iodine Contrast Media, Cisplatin and External Beam Radiotherapy on Anaplastic Thyroid Cancer Cells
Introduction: The current study investigated the combination of high Z atoms (iodine-, platinium-based drugs) with using low energy irradiation (120kvp) in Anaplastic Thyroid cancer cells. Material and Methods: For this...
Determination of TG-43 Dosimetric Parameters for Photon Emitting Brachytherapy Sources
Objective: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determina...