The Effect of Local Platelet Rich Plasma Therapy on the Composition of Bacterial Flora in Chronic Venous Leg Ulcer
Journal Title: Polish Journal of Microbiology - Year 2016, Vol 65, Issue 3
Abstract
Microbial colonisation of chronic venous ulcers and synergism between bacterial species slow down the healing process. The study aimed at performing qualitative analysis of microbial flora in venous leg ulcers treated with platelet rich plasma (PRP). Twenty two women and twelve men aged 47–90 years were treated with PRP at our department between 2012 and 2015. Ulcer cultures collected before and after PRP therapy yielded 83 and 110 microbial isolates, respectively, of Gram positive, Gram negative bacteria and candida. Pseudomonas aueruginosa and Staphylococcus aureus were the most common pre- and post-treatment isolates. PRP therapy and increased the variety of microbial flora.
Authors and Affiliations
Witold Woźniak, Monika Tarnas, Tomasz Miłek, Krzysztof R. Mlosek, Piotr Ciostek
The Diversity, Growth Promoting Abilities and Anti-microbial Activities of Bacteria Isolated from the Fruiting Body of Agaricus bisporus
Agaricus bisporus plays an important role in ecological processes and is one of the most widely cultivated mushrooms worldwide. Mushroom growth-promoting bacteria have been isolated from casing soil and compost, but micr...
Transferrin and Lactoferrin – Human Iron Sources for Enterococci
To overcome limitations in iron acquisition, enterococci have evolved a number of mechanisms to scavenge iron from the host iron-binding proteins – transferrin (TR) and lactoferrin (LF). The aim of this study was to demo...
<strong>Evaluation of the Time Period for Which Real-Time Polymerase Chain Reaction Detects Dead Bacteria</strong>
Real-time polymerase chain reaction (PCR) is currently used widely for the diagnosis of infectious diseases. We evaluated the time required for which real-time PCR can detect bacteria that had been killed [i]in vitro[/i]...
In Vitro Studies of Antibacterial and Antifungal Wound Dressings Comprising H<sub>2</sub>TiO<sub>3</sub> and SiO<sub>2</sub> Nanoparticles
The incidence rate of the infected and complex wound is established approximately 40 000/1 million of the world’s adult population. The aim of this study was to assess the efficiency of three novel types of wound dr...
<strong>Biochemical and Molecular Characterization of Carotenogenic Flavobacterial Isolates from Marine Waters</strong>
Carotenoids are known to possess immense nutraceutical properties and microorganisms are continuously being explored as natural source for production of carotenoids. In this study, pigmented bacteria belonging to [i]Flav...