THE EFFICACY OF EPIDURAL STEROID INJECTIONS IN THE MANAGEMENT OF PATIENTS WITH LUMBOSACRAL DEGENERATIVE SPINE DISEASES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 28
Abstract
BACKGROUND Degenerative diseases of the lumbosacral region are becoming a more frequent presentation to the clinician, particularly with the increasing ageing population worldwide. These conditions result in impingement of the nerve roots and inflammation, causing radiculopathy along the course of the affected nerve root. Epidural steroid injections are commonly employed to alleviate the radiculopathy when the use of conservative methods of treatment have failed. The objective of the study was to determine the efficacy of this treatment modality in our setting. MATERIALS AND METHODS This study was an observational study carried out at the Jos University Teaching Hospital, Nigeria. Patients who had epidural steroids within one-year period (July 2016 - June 2017), who were being managed for degenerative spine disease of the lumbosacral region were included in the study. The data was obtained from the case records of the patients. Epidural steroids were administered under sterile conditions. 80 mg of Methylprednisolone was used with 3 mL of 1% lignocaine. This was administered via the interlaminar route to the epidural space. The patients’ responses were assessed using the numeric pain scale (11-point scale from 10 to 0). Data was analysed using Statistical Package for Social Sciences (SPSS). Pain before the procedure, pain after the procedure and the pain differential on the scale were assessed as well as complications. The paired t-test was used to analyse the mean pain scores at 95% confidence interval and a p-value < 0.05 was considered statistically significant. RESULTS A total of 34 patients were involved in the study. 11 males and 23 females with a male: female ratio of 1: 2.1. The ages of the patients ranged from 20 to 80 years with a mean age of 57.2. The pathologies were disc degeneration and herniation 21 (61.8%), degenerative spondylolisthesis 6 (17.5%), spinal canal stenosis 4 (11.8%) and prolapsed intervertebral disc 3 (8.8%). The mean score before the procedure was 8.8 ± 0.81; 6 (17.6%) patients scored 10, 17 (50%) scored 9, 9 (26.5%) scored 8 and 2 (5.9%) scored 7. Mean pain scores after the procedure was 2.2 ± 1.34; 14 (41.2%) patients scored 1, 9 (26.5%) scored 2, 5 (14.7%) scored 3, 4 (11.8%) scored 4 and 1 each (2.9%) scored 5 and 6; 31 (85.3%) patients had a reduction by 50% or more in their pain scores. A statistically significant difference (t= 25.09; p < 0.000 at 95% confidence interval) was observed between the mean pain scores before and after epidural steroid injection. CONCLUSION Epidural steroid injections are a safe and effective method of treating patients with radiculopathy from lumbosacral degenerative spine diseases.
Authors and Affiliations
Ode M. B, Taiwo F. O, Amupitan I, Onoja A. A, Mancha D. G, Nkinyam G. Y
SYMPATHETIC OPHTHALMITIS AFTER LIMBAL CORNEAL TEAR REPAIR - A CASE STUDY
Sympathetic ophthalmia is a rare bilateral granulomatous inflammation that follows accidental or surgical insult to the uvea of one eye. In this study, we discuss a case of who presented after corneal tear repair...
FACTORS ASSOCIATED WITH EARLY INITIATION OF BREASTFEEDING AMONG MOTHERS OF DIBRUGARH DISTRICT, ASSAM- A COMMUNITY-BASED CROSS-SECTIONAL STUDY
BACKGROUND Early or timely initiation of breastfeeding, specifically within 1 hour of birth, refers to the best practice recommended by the World Health Organization (WHO). There is growing evidence of the significant im...
ON EFFICACY AND ACCEPTABILITY OF EARLY MEDICAL ABORTION BY MIFEPRISTONE WITH ORAL OR VAGINAL MISOPROSTOL
BACKGROUND Unsafe abortion is a major public health problem. Globally, 20 million unsafe abortions take place each year and account for 13% of all maternal deaths. According to WHO, 56% of abortions in developing countri...
A STUDY OF PERCUTANEOUS FIXATION OF DISPLACED SUPRACONDYLAR FRACTURE OF HUMERUS IN CHILDREN
BACKGROUND Closed reduction and percutaneous K-wire fixation is the standard modality of treatment in displaced supracondylar fractures of distal humerus in children. We report the result of a prospective study of fifty...
ACUTE APPENDICITIS IN PREGNANCY- CLINICAL FEATURES, DIAGNOSTIC MODALITIES AND MANAGEMENT
BACKGROUND Acute appendicitis is the most common non-obstetric surgical emergency during pregnancy accounting for 1 in 1500 deliveries with preponderance during the second trimester. Attention of the surgeons is often di...