The frequency of epicardial fat pads detected by chest x-rays in psoriasis patients
Journal Title: Turkderm-Turkish Archives of Dermatology and Venereology - Year 2020, Vol 54, Issue 4
Abstract
Background and Design: Psoriasis is a chronic inflammatory skin condition associated with several systemic comorbidities including cardiovascular diseases (CVD). Epicardial fat pad (EFP) is defined as a visceral fat tissue surrounding the heart and coronary vessels. Recent studies revealed epicardial fat thickness, which is also increased in psoriasis, as an early sign of CVD. The aim of this study was to evaluate EFP prevalence and its associations in psoriasis patients. Materials and Methods: Two hundred thirty-seven psoriasis and 113 control patients were assessed for CVD risk factors, Psoriasis Area Severity Index, body composition parameters and laboratory work-up. Controls were chosen from outpatients who lack any chronic inflammatory skin disease and/or systemic inflammatory disease. Evaluation of chest X-rays were performed by a radiologist who was unaware of clinical data. Results: 42.2% of psoriasis patients (n=100) and 31% of controls (n=35) had EFP detected on chest X-ray revealing psoriasis patients had significantly more prevalent EFP than the controls (p=0.047). Prevalence of major CVD risk factors was statistically higher in psoriasis patients (60%, n=142) compared to controls (32%, n=36), (p<0.01). Psoriasis patients with EFP presented higher prevalence of CVD risk factors (70%, 4, n=69) compared to patients who did not have EFP (53%, n=67) (p=0.009). Conclusion: EFP is associated with concurrent CVD risk factors and is more prevalent in psoriasis. It can be detected by a first-line imaging method like chest X-ray which is quite cheap, easy to perform and applicable to almost each patient.
Authors and Affiliations
Sibel Doğan, Pelin Esme, Meltem Gülsün Akpınar, Nilgün Atakan
Keywords
Related Articles
- EP ID EP691626
- DOI 10.4274/turkderm.galenos.2020.74240
- Views 124
- Downloads 0
Cutaneous manifestations in children patients with type 1 diabetes mellitus
Background and Design: Type 1 diabetes mellitus (T1DM) can cause significant changes in the skin. However, there are limited studies examining the skin findings in children with T1DM. The objective of this study is to de...
Evaluation of cutaneous manifestations in patients under treatment with thyroid disease
Background and Design: Thyroid diseases often cause various findings in hair, skin and nails. Some of them may be regressed by the treatment of thyroid disease. We aimed to evaluate the cutaneous manifestations in patien...
Complex aphthosis-like pemphigus vulgaris during pregnancy
No summary
Changes in the expression pattern of epidermal stem cell markers in acute and chronic psoriatic lesions
Background and Design: The characteristic morphology of skin is maintained by the self-renewal of epidermal stem cells located in the basal layer and in hair follicles in skin diseases. In this study, we tried to determi...
Need for patient education and better physician-patient communication in melanoma patients: Behaviors and knowledge of melanoma patients
Background and Design: Melanoma is a serious type of cancer. Patients previously diagnosed with melanoma are at an increased risk of a second melanoma. Therefore, it is important to know and apply preventive measures. Th...