The impact of different 75 g oral glucose tolerance test target ranges within normal limits on neonatal outcomes: A validation study
Journal Title: Turkish Journal of Obstetrics and Gynecology - Year 2018, Vol 15, Issue 1
Abstract
Objective: To investigate the impact of different 75 g glucose tolerance test (OGTT) target ranges within normal limits on neonatal outcomes, thus to investigate the validity of 75 g OGTT thresholds. Materials and Methods: The normal 1-hour and 2-hour ranges of 75 g OGTT levels of 110 pregnant women with no gestational diabetes mellitus (GDM) were further divided into three different sub-groups; for the 1 hour as group 1 (<120 mg/dL), group 2 (120-140 mg/dL), group 3 (>140 mg/dL) and for the 2 hour as group 1 (<120 mg/dL), group 2 (120-135 mg/dL), and group 3 (>135 mg/dL). Results: For the 1-hour results, there was no statistically significant difference between groups in terms of age, body mass index, multiparity, neonatal hypoglycemia, hyperbilirubinemia, neonatal intensive care unit admission, birth weight, and LGT rates; however, the rate of small-for-gestational-age (SGA) infants was significantly higher in group 2 compared with those in group 3. For the 2-hour results, statistically similar results were found between the groups. Conclusion: A 2-hour 75 g OGTT has reliable threshold values for GDM screening. However, because there are still adverse neonatal outcomes in women with OGTT results below the current thresholds and the number of SGA fetuses is higher in the glucose range 120-140 mg/dL of the first hour, the validity of the 75 g OGTT thresholds still needs further investigation.
Authors and Affiliations
Seda Subaş, Gökçe Anık İlhan, Zehra Meltem Pirimoğlu
Keywords
Related Articles
- EP ID EP365298
- DOI 10.4274/tjod.40370
- Views 108
- Downloads 0
Pelvic floor disorders associated with higher-level sexual dysfunction in the Kersa district, Ethiopia
Objective: To assess the prevalence of female sexual dysfunction and its association with pelvic floor disorder (PFD) in a large scale, community-based study. Materials and Methods: A total of 2389 women who were married...
Post-cesarean scar endometriosis
Objective: Endometriosis is seen in women during their reproductive period, where stromal tissue and functional endometrial glands of the uterus are observed outside the uterine cavity. In this study, we aimed to identif...
Spectroscopic analysis of embryo culture media for predicting reproductive potential in patients undergoing in vitro fertilization
Objective: To predict the reproductive potential of embryos via Raman spectroscopy evaluation of the spent culture media as well as with a conventional morphologic evaluation. Materials and Methods: Women of reproductiv...
Management of vesicovaginal fistulas after gynecologic surgery
Objective: In developed nations, surgery, especially gynecologic procedures, is the major cause of vesicovaginal fistulas (VVFs). We retrospectively evaluated our treatment modalities for VVF repair caused by a gynecolog...
Diagnostic sign of intra uterine extra amniotic adhesions with 4D ultrasonography: Sheet on string
.