The pharmacoeconomic analysis of the pharmacotherapy regimens for the irritable bowel syndrome using the “cost minimization” method
Journal Title: Клінічна фармація; Клиническая фармация - Year 2019, Vol 23, Issue 2
Abstract
Irritable bowel syndrome (IBS) is a clinical pathology accompanied with a significant physical and psychological discomfort, and leading to certain economic losses. Women suffer from IBS 2.2 times more often than men. Aim. To conduct a comparative analysis of drugs recommended for treating patients with IBS by minimizing costs and choosing the treatment regimens allowing to save money with the same efficacy of therapy. Materials and methods. The cost minimization analysis (CMA) of drugs was conducted using data on the cost of drugs for 2018. The course of the primary pharmacotherapy was calculated on the combination of antispasmodic and Loperamide and lasted for 4 weeks (28 days). Results. For the treatment of IBS the combination of a diet, pharmacotherapy and psychotherapy is important. Therefore, for calculation the treatment regimen with two drugs – an antispasmodic and Loperamide was used for IBS with a predominance of diarrhea. After analyzing the cost of treatment regimens we can note that the cheapest regimen with INN Mebeverin was the regimen with drugs Aspasmin and Loperamide hydrochloride. The total cost of the regimen was UAH 287.94. Otilonium bromide is represented by only one TN, and the final price of the treatment regimen with this drug depends on Loperamide. The treatment regimen with Loperamide hydrochloride of the Ukrainian production (UAH 320.65 per course) appeared to be cheaper. The cheapest treatment regimen with Drotaverin was the one with two drugs of domestic production – NO-KH-SHA® and Loperamide hydrochloride (141.01 UAH). Conclusions. It has been determined that the difference in costs for different treatment regimen depends on the price of drugs, as well as on whether it is generic or original (brand), imported or domestic drug. Most domestic drugs are generic; therefore, the treatment regimens will be cheaper and will help to save money.
Authors and Affiliations
D. V. Zakorko, T. O. Baglay
Keywords
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- EP ID EP657958
- DOI 10.24959/cphj.19.1496
- Views 94
- Downloads 0
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