The prevalence and clinico-microbiological profile of spontaneous bacterial peritonitis in chronic liver disease
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Ascites is the most common complication of cirrhosis. Ascitic fluid can become infected without any apparent intra-abdominal source of infection, a condition called Spontaneous bacterial peritonitis. A hospital based cross-sectional study was conducted in 200 patients of chronic liver disease with ascites admitted in the Department of Medicine, RIMS, Imphal between September 2016 and August 2018, to find the prevalence and clinico-microbiological profile of spontaneous bacterial peritonitis. All patients underwent diagnostic paracentesis after giving consent. 42 out of 200 patients, i.e. 21% were found to have SBP, out of which 2 (5%) were female and 40 (95%) were male. 35 (83.33%) patients had Culture Negative Neutrocytic ascites (CNNA), 6 (14.28%) had Classical SBP and 1 (2.38%) had Bacterascites. Most of them were gram negative, mainly Escherichia coli n=5 (71.42%), Klebsiella pnuemoniae n=1 (14.28%) and Staphyloccus aureus n=1 (14.28%). Most organisms isolated were susceptible to ceftriaxone. The most common presenting feature in SBP patients was fever (88.09%), abdominal pain (85.71%), jaundice (71.42%), hepatic encephalopathy (69.04%) and UGI bleed (28.57%). Therefore, the prevalence of Spontaneous bacterial peritonitis is 21% with Escherichia coli being the commonest organism in this setting. History of alcohol consumption, abdominal pain, fever, low ascitic fluid total protein, high indirect bilirubin and low serum protein were found to be predictors of spontaneous bacterial peritonitis.
Authors and Affiliations
Levica Kahit, N Biplab Singh, Ksh Birendra Singh, Kh Sulochana Devi, Wungreipam Kasar
Keywords
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- EP ID EP432598
- DOI 10.9790/0853-1801056371.
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