Abstract

Objective: Contrast nephropathy (KMN) is defined as an acute renal injury due to intravenous contrast agents applied in diagnostic or therapeutic interventions and is an important cause of hospitalization due to acute renal failure. In this study, the frequency of coronary intervention and contrast agent nephropathy was investigated in acute coronary syndrome. Material and Method: According to the European Urogenital Radiology Society Guide, “An increase of 25 or 0.5 mg/dl in serum creatinine within 3 days after administration of contrast medium without any other etiological cause”. After approval of the Ethics Committee, 336 patients who met the inclusion criteria were included in the study. Patients younger than 18 years of age with chronic renal insufficiency, heart failure, coronary by-pass history, serum creatinine control after the procedure and patients without percutaneous coronary intervention were excluded from the study. Results: BMD was detected in 11.9% of the 336 patients included in the study. The mean age of 40 patients who developed CMN was 73.9±10.2 / year, and the mean age of 296 patients who did not have CMN was 59.4±12.3 /year. The mean age was significantly higher in the DM group (p <0.001). The mean body mass index (BMI) was 28.2 ± 4.7kg / m² in the non-developing group, while the BMI average was 26.5 ± 3.3kg / m². The mean VKI was lower in the DM group (p = 0.044). The mean SYNTAX score was 16.6 ± 8.3 in the nondeveloping group, whereas the mean in the group with the improved KMN was 22.5 ± 10.3. The SYNTAX score was higher in the KMN-developing group than in the non-KMN group (p=0.001). There was no difference between two groups in terms of AKS type, DM, HT and sex (p=0.713, p=0.317, p=0.055, p=0.589). Conclusion: Strategies should be implemented to prevent other CMD developments, provided that hydration is absolute before and after the procedure in groups at risk for which contrast media should be given.

Authors and Affiliations