The Prevalence of Δ508 in Cystic Fibrosis Patients with Low Bone Mineral Density in Republic of Macedonia
Journal Title: International Journal of Science and Research (IJSR) - Year 2015, Vol 4, Issue 1
Abstract
Introduction: Reduced bone mass density (BMD) is frequent in patients with cystic fibrosis (CF). Pathogenesis of CF bone disease is multifactorial. Many studies suggest that there is genetic component, independent of the disease severity and nutritional deficits. Aim: To determine the prevalence and identify determinants of reduced BMD in CF patients. Material and methods: The study included 80 CF patients (range 5-36y.). BMD was measured via dual-energy x-ray absorptiometry (DXA) scan. Vitamin D level was assessed by plasma 25OHD levels (
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